Q2L1L0
Gene name |
pckG |
Protein name |
Phosphoenolpyruvate carboxykinase [GTP] |
Names |
PEP carboxykinase, PEPCK |
Species |
Bordetella avium (strain 197N) |
KEGG Pathway |
bav:BAV1626 |
EC number |
4.1.1.32: Carboxy-lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2L1L0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2L1L0-F1 | Predicted | AlphaFoldDB |
No variants for Q2L1L0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2L1L0 | |||||
No associated diseases with Q2L1L0
3 regional properties for Q2L1L0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site | 273 - 281 | IPR018091 |
| domain | Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain | 249 - 614 | IPR035077 |
| domain | Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal | 25 - 245 | IPR035078 |
Functions
| Description | ||
|---|---|---|
| EC Number | 4.1.1.32 | Carboxy-lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| manganese ion binding | Binding to a manganese ion (Mn). |
| phosphoenolpyruvate carboxykinase (GTP) activity | Catalysis of the reaction: GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO2. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| gluconeogenesis | The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTQAAEATLP | PLNVPSYVKH | ARLIDWVQGV | VALTKPARVV | WCDGSQEEAD | RLCEQMVQAG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TMRRLNPAKR | PNSYLAWSDP | SDVARVEDRT | FICSQREEDA | GPTNNWAAPA | EMRNTLQGLF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DGAMRGRTLY | VVPFSMGPLG | SPIAHIGVEL | SDSPYVAVNM | RIMTRMGRAV | WDVLGADGEF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VPCVHSVGMP | LAEGQADVAW | PCNPVKYIVH | YPETREIWSF | GSGYGGNALL | GKKCFALRIA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| STMGRDEGWL | AEHMLILGVT | TPKGRKFHVA | AAFPSACGKT | NFAMLIPPSG | MDGWKVSTIG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DDIAWIKPGQ | DGRLRAINPE | AGYFGVAPGT | SEKTNPNAMA | TLKANVIFTN | VALTDDGDVW |
| 370 | 380 | 390 | 400 | 410 | 420 |
| WEGMTDTPPA | HLIDWQGKDW | TPEIARETGR | KAAHPNARFT | APASQCPSID | PEWENPQGVA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IDAFIFGGRR | STTIPLVTEA | RDWVQGVYMA | ATMGSETTAA | AVGQQGVVRR | DPFAMLPFCG |
| 490 | 500 | 510 | 520 | 530 | 540 |
| YNMADYFNHW | LAVGQRLADA | GATLPRIYCV | NWFRKGPNGK | FVWPGFGENM | RVLKWMLGRL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| SGEAGGQEQV | FGISPSYGDV | DWTGLEFTPD | QFQQVISVEA | PAWREELALH | GELFEQLAQG |
| 610 | 620 | ||||
| LPPALSRAKA | DIEHRLAAVQ | A |