Q2KHS5
Gene name |
mogat2-a |
Protein name |
2-acylglycerol O-acyltransferase 2-A |
Names |
Acyl-CoA:monoacylglycerol acyltransferase 2-A, MGAT2-A, Monoacylglycerol O-acyltransferase 2-A |
Species |
Xenopus laevis (African clawed frog) |
KEGG Pathway |
xla:735031 |
EC number |
2.3.1.20: Transferring groups other than amino-acyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2KHS5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2KHS5-F1 | Predicted | AlphaFoldDB |
No variants for Q2KHS5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2KHS5 | |||||
No associated diseases with Q2KHS5
No regional properties for Q2KHS5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q2KHS5 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.1.20 | Transferring groups other than amino-acyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| perinuclear endoplasmic reticulum membrane | The membrane of the perinuclear endoplasmic reticulum, which is the portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| 2-acylglycerol O-acyltransferase activity | Catalysis of the reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| glycerol metabolic process | The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. |
| monoacylglycerol biosynthetic process | The chemical reactions and pathways resulting in the formation of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified. |
| triglyceride biosynthetic process | The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKIQFAPHNV | PFERRLQTAA | VLQWVFSFLA | LAQTCILLFF | VLLFTRFWII | SVVYGVWWFL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DWDTPSKGGR | RGEWLRRHVI | WTYMKDYFPI | TLVKTADLDP | QQNYVVGSHP | HGVLVAGAFT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NFCTEATGFH | RLFPGITPYL | LMLPLWFRAP | FFRDYIMSGG | LIPSDKDSAS | YLLKNKAGGN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AVVIAVGGAP | ESLDARPGAF | TLLIKNRKGF | VRLAILHGAS | LVPVFSFGEN | ELFDQVDNPR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GSWLRKIQEK | LQKMMGVALP | LFHARGVFQY | SFGLIPYRKP | IATIVGKPIR | VEENPNPSSE |
| 310 | 320 | 330 | |||
| EVDKLHKIYM | EELSKLFEEH | KTKYNVPADK | HLTFV |