Q2KE98

PR
Gene name
coaE
Protein name
Dephospho-CoA kinase
Names
Dephosphocoenzyme A kinase
Species
Rhizobium etli (strain CFN 42 / ATCC 51251)
KEGG Pathway
ret:RHE_CH00004
EC number
2.7.1.24: Phosphotransferases with an alcohol group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

109-182 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2KE98

Entry ID Method Resolution Chain Position Source
AF-Q2KE98-F1 Predicted AlphaFoldDB

No variants for Q2KE98

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2KE98

No associated diseases with Q2KE98

3 regional properties for Q2KE98

Type Name Position InterPro Accession
domain Calcineurin-like phosphoesterase domain, ApaH type 122 - 322 IPR004843
domain Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase 94 - 385 IPR006186
domain PP2B, metallophosphatase domain 79 - 383 IPR041751

Functions

Description
EC Number 2.7.1.24 Phosphotransferases with an alcohol group as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
dephospho-CoA kinase activity Catalysis of the reaction: 3'-dephospho-CoA + ATP = ADP + CoA + 2 H(+).

2 GO annotations of biological process

Name Definition
coenzyme A biosynthetic process The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLKIGLTGSI GMGKSTVGKL FAEAGIPLND SDAVVHNLYA GEAAPLVNAA FPGTMKDGAV
70 80 90 100 110 120
DRHELGRQLA LDPEGFKRLE AIVHPLVRKR EMEFLAKQQA DGAEMVLLDI PLLFETGAWE
130 140 150 160 170 180
RVDVIVVVST DSQIQRQRVL AREDMTEEKF DMILSRQTPD AEKRRRADYL VDTSHSIAET
190 200
RAQVLEIIAE LKMRIAKGDF RNA