Q2K5Q0

PR
Gene name
clpP3
Protein name
ATP-dependent Clp protease proteolytic subunit 3
Names
Endopeptidase Clp 3
Species
Rhizobium etli (strain CFN 42 / ATCC 51251)
KEGG Pathway
ret:RHE_CH03069
EC number
3.4.21.92: Serine endopeptidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-47 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2K5Q0

Entry ID Method Resolution Chain Position Source
AF-Q2K5Q0-F1 Predicted AlphaFoldDB

No variants for Q2K5Q0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2K5Q0

No associated diseases with Q2K5Q0

9 regional properties for Q2K5Q0

Type Name Position InterPro Accession
domain AAA+ ATPase domain 199 - 344 IPR003593-1
domain AAA+ ATPase domain 600 - 758 IPR003593-2
domain ATPase, AAA-type, core 204 - 308 IPR003959-1
domain ATPase, AAA-type, core 599 - 751 IPR003959-2
domain Clp, repeat (R) domain 1 - 147 IPR004176
conserved_site ClpA/B, conserved site 1 296 - 308 IPR018368
domain Clp ATPase, C-terminal 757 - 846 IPR019489
conserved_site ClpA/B, conserved site 2 634 - 652 IPR028299
domain ClpA/ClpB, AAA lid domain 344 - 446 IPR041546

Functions

Description
EC Number 3.4.21.92 Serine endopeptidases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP-dependent peptidase activity Catalysis of the hydrolysis of peptide bonds, driven by ATP hydrolysis.
serine-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNDEEQDDKT KELPLGKETE ANLFKSRSIF IYGPINQELA QKVCSQLVAL AAASDEDIRI
70 80 90 100 110 120
YVNSPGGHVE SGDSIHDMVK FIKPKVWMIG TGWVASAGAL IYVAAPRERR LCLPNTRFLL
130 140 150 160 170 180
HQPSGGTRGM ASDIEIQARE IIKMNERLNK IMAEATGQPL EKIAKDTDRD YWLSAEEAKD
190
YGLVSRIVTS QADI