Q2K4C4
Gene name |
hemH |
Protein name |
Ferrochelatase |
Names |
Heme synthase, Protoheme ferro-lyase |
Species |
Rhizobium etli (strain CFN 42 / ATCC 51251) |
KEGG Pathway |
ret:RHE_CH03556 |
EC number |
4.98.1.1: Forming coordination complexes |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2K4C4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2K4C4-F1 | Predicted | AlphaFoldDB |
No variants for Q2K4C4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2K4C4 | |||||
No associated diseases with Q2K4C4
1 regional properties for Q2K4C4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Uroporphyrinogen decarboxylase (URO-D) | 19 - 366 | IPR000257 |
Functions
| Description | ||
|---|---|---|
| EC Number | 4.98.1.1 | Forming coordination complexes |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ferrochelatase activity | Catalysis of the reaction: heme B (protoheme) + H+ = Fe(2+) + protoporphyrin IX. |
| metal ion binding | Binding to a metal ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| heme biosynthetic process | The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTADISLRPA | DHPAIKSGKI | GVLLVNLGTP | DGTDYTSMRR | YLKEFLTDRR | VIEWSPWKWY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PILFGIVLNT | RPQKVGKAYE | LIWNKEKNES | YLRTYTRNQA | ELMAKRLHDL | ANVKVDWAMR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YGTPSIASRI | ETLKQEGCDR | ILLFPLYPQY | AAATTATVND | KAFQKLLSMR | WQPALRTVPD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YHDDETYIEA | LAQSVERHLS | SLDWKPDMLL | ASFHGIPMSY | FKQGDPYYCQ | CQKTGRLLRE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RLGLTQENFM | VTFQSRFGPE | EWLQPYTDKT | VEKLAQDGVK | RIAVINPGFV | SDCLETLEEI |
| 310 | 320 | 330 | 340 | ||
| AEQAAHSFHE | NGGDKFTHIP | CLNDSDDGMK | VLEKVVRREL | QGWV |