Q2JW99

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacterium Yellowstone A-Prime)
KEGG Pathway
cya:CYA_0762
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

894-954 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2JW99

Entry ID Method Resolution Chain Position Source
AF-Q2JW99-F1 Predicted AlphaFoldDB

No variants for Q2JW99

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2JW99

No associated diseases with Q2JW99

7 regional properties for Q2JW99

Type Name Position InterPro Accession
domain SecA DEAD-like, N-terminal 5 - 382 IPR011115
domain SecA Wing/Scaffold 704 - 916 IPR011116
domain SecA, preprotein cross-linking domain 227 - 338 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 88 - 246 IPR014001
domain SecA motor DEAD 2 - 706 IPR014018
conserved_site SecA conserved site 482 - 497 IPR020937
domain SecA, C-terminal helicase domain 400 - 676 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cellular thylakoid membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
plasma membrane-derived thylakoid membrane The pigmented membrane of a plasma membrane-derived thylakoid.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLQALQKLLG DPNERKIRKY LPVVKLINSL EIEIASLSDA ELRAKTTEFR QRLDRGESLD
70 80 90 100 110 120
DLLPEAFAVV REAAKRVLNL RHYDVQLIGG MVLHEGQIAE MKTGEGKTLV ATLPAYLNGL
130 140 150 160 170 180
TGKGVHIVTV NGYLARRDSE WMGQVHRFLG LTVGLVQEGM STDEKRRSYH CDITYCTNSE
190 200 210 220 230 240
LGFDYLRDNM ATDIKEVMQR PFNYCIIDEV DSILIDEART PLIISGQMAR PSEKYLKAAQ
250 260 270 280 290 300
VARELIRDEH YEVDEKARNV ILTDEGFEAA ERLLGVSDLF DPKDPWAHFV FNAVKAKELF
310 320 330 340 350 360
IRDVHYIVRN QEVVIVDEFT GRVLPGRRWS DGLHQAVEAK EGVPIQNESQ TLATITYQNL
370 380 390 400 410 420
FLLYPKLSGM TGTARTEEAE FSKTYNLEVT VIPTNRPIRR KDAPDLVYKT ENAKWKAVAE
430 440 450 460 470 480
EIAHMHAQGR PVLVGTTSVE KSERLSAMLK EMGIPHNLLN AKPENVEREA EIIAQAGRKG
490 500 510 520 530 540
AVTIATNMAG RGTDIILGGN AEYMARLKLR ERLMPKLVQL DPDNPLGSAS TTSRGGGQGF
550 560 570 580 590 600
GPASPKPKKS WTVVSPNFYP CELSARTSQA LDEVVAAAVA KYGLNRLPEL VVEDLIAVAS
610 620 630 640 650 660
EKAPVQDPLI LQLREVYNSI KAEYEKVTEA EHEEVVRLGG LHVIGTERHE SRRIDNQLRG
670 680 690 700 710 720
RAGRQGDPGS SRFFLSLEDN LLKIFGGERV AKLMDMFRVD EDMPIEHPLL SSSLENAQRK
730 740 750 760 770 780
VEVYYFDLRK QVFEYDEVMN NQRRAIYSER RRILEGENLK PKILDYMRKT VEEIVRAHVN
790 800 810 820 830 840
PELPPEEWEI DKLTAKMQEF VPLLKENLKA DDLRDLSYQE ILDHLIKQAE LAYEAKEAFL
850 860 870 880 890 900
DTFEPGLMRK AERFFLLQQV DTLWREHLQQ MEALREAVGL RGYGQRDPLI EYKNEGYELF
910 920 930 940 950
LEMMDNIRRN TVYNLFVFTP QLVQVPQVAQ AVPAQAVAAS PETGGVVEAD FAED