Q2JT35

PR
Gene name
mutS
Protein name
DNA mismatch repair protein MutS
Names
Species
Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacterium Yellowstone A-Prime)
KEGG Pathway
cya:CYA_2035
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

798-879 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2JT35

Entry ID Method Resolution Chain Position Source
AF-Q2JT35-F1 Predicted AlphaFoldDB

No variants for Q2JT35

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2JT35

No associated diseases with Q2JT35

5 regional properties for Q2JT35

Type Name Position InterPro Accession
domain DNA mismatch repair protein MutS, C-terminal 634 - 822 IPR000432
domain DNA mismatch repair protein MutS-like, N-terminal 7 - 119 IPR007695
domain DNA mismatch repair protein MutS, core 292 - 615 IPR007696
domain DNA mismatch repair protein MutS, connector domain 127 - 262 IPR007860
domain DNA mismatch repair protein MutS, clamp 452 - 543 IPR007861

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.
damaged DNA binding Binding to damaged DNA.
mismatched DNA binding Binding to a double-stranded DNA region containing one or more mismatches.

1 GO annotations of biological process

Name Definition
mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDPALLTPMM QHYVELKRQY PHAILLYRLG DFYEMFFQDA QLVSRELELV LTGREAGAIG
70 80 90 100 110 120
RVPMCGIPYH AFDRYAAQLV AKGYALAVCD QMEPADQAKG LVRREVTRVI TPGTVIEEEL
130 140 150 160 170 180
LQARQNNYLA AIVRLRGSKQ TVWGLAYADI STGEFWVCQG EGQEQLEQEL ARLQPAEILL
190 200 210 220 230 240
PTEEGLGLGL MRPGDPQAPL GLPGQYTYTL RPAEPFELAT ARENLLQTYG LRSLEGLGCE
250 260 270 280 290 300
GLPLAIRAAG GLLHYLEETQ KNLVQPSPQG GHPLLRPPRT YQLTDYLILD TQTRRNLELT
310 320 330 340 350 360
QTIREGAFVG SLLWVLDRSR TAMGGRTLRR WLLQPLRDPE QIRLRQDTIQ ELLESPSLRT
370 380 390 400 410 420
RLGSLLDSLY DLERLANRVA SGTANPRELV ALGSSLGKLP QLAELVAEAQ TPLLQSLQQV
430 440 450 460 470 480
DPALVDLGHR IEHTLLPSPP PVLTEGGLIR PGVDAELDRL RQQVEQDRHW IAQLEKTERE
490 500 510 520 530 540
RTGIPTLKVG FNKAFGYYLS ISRAKAQQVP KEYIRKQTLT NEERFITPEL KEKEARILTA
550 560 570 580 590 600
QTEINQREYE LFVQLRQEAG SQAAAIRQVA QTLAAVDALF GLAEVAVQQG YTRPVITADR
610 620 630 640 650 660
RLIIEEGRHP VVEKSLPQGL FVPNSVRLGS PHGPDLIVLT GPNMSGKSTY LRQIGLIQIL
670 680 690 700 710 720
AQMGSFVPAR RAELGLCDRV FTRIGAVDDL ATGQSTFMVE MNETANILNH AGERSLVLLD
730 740 750 760 770 780
EIGRGTATFD GLSIAWAVAE YLATQVRART IFATHYHELN QLETLLPNVA NFQVVVKELR
790 800 810 820 830 840
DRIIFLHQVQ PGGADRSYGI EVGRMAGLPQ PVIERAKQVL ALVEQHSRIG LGLRSQGKSR
850 860 870 880
PSSNNPKKRF KQESNSRGIP DCDAKAGDQL SLIPTSLYPE EL