Q2JQT5

PR
Gene name
rpoC1
Protein name
DNA-directed RNA polymerase subunit gamma
Names
RNAP subunit gamma, RNA polymerase subunit gamma, Transcriptase subunit gamma
Species
Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacterium Yellowstone A-Prime)
KEGG Pathway
cya:CYA_0410
EC number
2.7.7.6: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

177-248 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2JQT5

Entry ID Method Resolution Chain Position Source
AF-Q2JQT5-F1 Predicted AlphaFoldDB

No variants for Q2JQT5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2JQT5

No associated diseases with Q2JQT5

5 regional properties for Q2JQT5

Type Name Position InterPro Accession
domain RNA polymerase, alpha subunit 352 - 400 IPR000722-1
domain RNA polymerase, alpha subunit 402 - 493 IPR000722-2
domain RNA polymerase, N-terminal 243 - 522 IPR006592
domain RNA polymerase Rpb1, domain 3 497 - 620 IPR007066
domain RNA polymerase Rpb1, domain 1 6 - 350 IPR007080

Functions

Description
EC Number 2.7.7.6 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.

4 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
magnesium ion binding Binding to a magnesium (Mg) ion.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKTEQRFDY VKIGLASPER IIEWGQRTLP NGQVVGEVTK PETINYRTLK PEMDGLFCER
70 80 90 100 110 120
IFGPVKDWEC HCGKYKRVRH RGIVCERCGV EVTESRVRRH RMGYIKLAAP VTHVWYLKGI
130 140 150 160 170 180
PSHIATLLDM PLRDVEQVVY FNAYVVVDPG NAPNLSYKQL LTEDQYLEIE DQMYEEGSEL
190 200 210 220 230 240
QLPENWAMIG AEAIERLLKD IDLEKEAEQL REEIASARGQ KRARLIKRLR VIDNFIATGA
250 260 270 280 290 300
RPEWMVLRVL PVIPPDLRPM VQLDGGRFAT SDLNDLYRRV INRNNRLARL QEIMAPEIIV
310 320 330 340 350 360
RNEKRMLQEA VDALIDNGRR GRMVVGANNR PLKSLSDIIE GKQGRFRQNL LGKRVDYSGR
370 380 390 400 410 420
SVIVVGPNLR MHQCGLPKEM AIELFQPFVI HKLIKRGIVN NIKAAKKLIQ SNDPQVWDVL
430 440 450 460 470 480
EDVIDGHPVL LNRAPTLHRL GIQAFEPILV EGRAIQLHPL VCPAFNADFD GDQMAVHVPL
490 500 510 520 530 540
SLEAQAEARL LMLATNNILS PATGAPIITP SQDMVLGCYY LTADNPHAPD LGDRYFASLE
550 560 570 580 590 600
DALIAYDRGV IGLHSKIWVR YSGPMELGKE EKESEPQIIE EPGGTRLKIT NYRRIREDRD
610 620
GNVISQYIRT TAGRIIFNKT VQDILSA