Q2J2J4

PR
Gene name
pnp
Protein name
Polyribonucleotide nucleotidyltransferase
Names
Polynucleotide phosphorylase, PNPase
Species
Rhodopseudomonas palustris (strain HaA2)
KEGG Pathway
rpb:RPB_0605
EC number
2.7.7.8: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

659-718 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2J2J4

Entry ID Method Resolution Chain Position Source
AF-Q2J2J4-F1 Predicted AlphaFoldDB

No variants for Q2J2J4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2J2J4

No associated diseases with Q2J2J4

9 regional properties for Q2J2J4

Type Name Position InterPro Accession
domain Exoribonuclease, phosphorolytic domain 1 14 - 145 IPR001247-1
domain Exoribonuclease, phosphorolytic domain 1 326 - 456 IPR001247-2
domain S1 domain 625 - 698 IPR003029
domain K Homology domain 555 - 623 IPR004087
domain K Homology domain, type 1 559 - 619 IPR004088
domain Exoribonuclease, phosphorolytic domain 2 148 - 212 IPR015847-1
domain Exoribonuclease, phosphorolytic domain 2 461 - 532 IPR015847-2
domain Polyribonucleotide nucleotidyltransferase, RNA-binding domain 244 - 323 IPR015848
domain RNA-binding domain, S1 626 - 698 IPR022967

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFNKHSVEID WGGRPLKLET GKVARQADGA VVATYGETIV LATVVAAKTP REGVDFLPLT
70 80 90 100 110 120
VDYQEKTYAA GRIPGGYFKR EGRPTEKETL VSRLIDRPIR PLFADGWRNE TQVIVTVLSH
130 140 150 160 170 180
DMENDPDILA MVAASAALTL SGAPFKGPIG AARVGFINDE YVLNPVLDEM PETQLELVVA
190 200 210 220 230 240
GTADAVLMVE SEAKELSEEI MLGAVMFGHR HFQPVIDAII ELAEKAAKEP RELVVIDDSA
250 260 270 280 290 300
IEKEMLGLVE QELRAAYAIP VKQERYAAVG KVKEKAIAHF FPEGEEPKYD KLRIAGVFKE
310 320 330 340 350 360
LEAKIVRWNI LDTGKRIDGR DSKTVRSIIA EAGVLPRAHG SALFTRGETQ ALVVTTLGTG
370 380 390 400 410 420
EDEQYVDSLA GTYKETFLLH YNFPPYSVGE TGRLGGTKRR EIGHGKLAWR AIRPVLPPHH
430 440 450 460 470 480
EFPYTIRVVS EITESNGSSS MASVCGASLA LMDAGVPLKR PTAGIAMGLI LEGERFAVLS
490 500 510 520 530 540
DILGDEDHLG DMDFKVAGTE QGITSLQMDI KIAGITEEIM KVALGQAKDG RIHILGEMSK
550 560 570 580 590 600
ALDRARAELG EHAPRIETFK IPTDKIREVI GTGGKVIREI VEKTGAKVNI EDDGTVKVAS
610 620 630 640 650 660
SDGESIKAAI KWIKSIASDP EVGEIYEGTV VKVMEFGAFV NFFGAKDGLV HISQLASGRV
670 680 690 700 710
QKTSDVVKEG DKVKVKLLGF DDRGKTRLSM RVVDQETGED LEAKQKAEGE APAQATGE