Q2IXR9

PR
Gene name
rpoC
Protein name
DNA-directed RNA polymerase subunit beta'
Names
RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'
Species
Rhodopseudomonas palustris (strain HaA2)
KEGG Pathway
rpb:RPB_2286
EC number
2.7.7.6: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1342-1400 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2IXR9

Entry ID Method Resolution Chain Position Source
AF-Q2IXR9-F1 Predicted AlphaFoldDB

No variants for Q2IXR9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2IXR9

No associated diseases with Q2IXR9

6 regional properties for Q2IXR9

Type Name Position InterPro Accession
domain RNA polymerase, alpha subunit 346 - 487 IPR000722
domain RNA polymerase, N-terminal 237 - 516 IPR006592
domain RNA polymerase Rpb1, domain 3 491 - 644 IPR007066
domain RNA polymerase Rpb1, domain 1 18 - 344 IPR007080
domain RNA polymerase Rpb1, domain 5 762 - 1309 IPR007081
domain RNA polymerase Rpb1, domain 4 673 - 759 IPR007083

Functions

Description
EC Number 2.7.7.6 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.

4 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
magnesium ion binding Binding to a magnesium (Mg) ion.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNQEIMNLFN PTTPAQVFDQ IRISIASPEK ILSWSYGEIK KPETINYRTF KPERDGLFCA
70 80 90 100 110 120
RIFGPIKDYE CLCGKYKRMK YKGIICEKCS VEVTLSRVRR ERMGHIELAA PVAHIWFLKS
130 140 150 160 170 180
LPSRIGQLLD MTLKDLERIL YFEYYVVLEP GLTDLKERQL LSEEEYLRAQ DQYGQDSFTA
190 200 210 220 230 240
MIGAEAIREL LKGLELEKID AQLRVEMAET DSDIKHKKLA KRLKIVEAFR FSGNKPEWMI
250 260 270 280 290 300
LTVVPVIPPD LRPLVPLDGG RFATSDLNDL YRRVINRNNR LKRLMELRAP DIIIRNEKRM
310 320 330 340 350 360
LQEAVDALFD NGRRGRVITG ANKRPLKSLA DMLKGKQGRF RQNLLGKRVD YSGRSVIVVG
370 380 390 400 410 420
PELKLHQCGL PKKMALELFK PFIYSRLDAK GLSTTVKQAK KLVEKERPEV WDILDEVIRE
430 440 450 460 470 480
HPVLLNRAPT LHRLGIQAFE PVLIEGKAIQ LHPLVCAAFN ADFDGDQMAV HVPLSLEAQL
490 500 510 520 530 540
EARVLMMSTN NILHPANGQP IIVPSQDIVL GLYYLSILRE GLPGEGKVFG DLAELEHALF
550 560 570 580 590 600
SKVIHLHTKI KYRWDSLDDE GKPYQRLIET TAGRILLGQV LPKSVKLPFE VINKLMTKRE
610 620 630 640 650 660
ISSVIDQVYR HCGQKETVIF CDRIMALGFF NAFKAGISFG KDDMVVPASK WKIVDTTRTL
670 680 690 700 710 720
AKDFEQQYND GLITHGEKYN KVVDAWSKAT EEIAKEMMKE ISAVRKNASG AETQVNSIYM
730 740 750 760 770 780
MAHSGARGSP AQMRQLAGMR GLMAKPSGEI IETPIISNFK EGLSVLEYFN STHGARKGLA
790 800 810 820 830 840
DTALKTANSG YLTRRLVDVA QDCIITQDDC GTSLGIKMRA IIDAGTVVAS LGSRILGRTA
850 860 870 880 890 900
GEDVRDPQTN EVIVKKGQLM EERDVEAIHQ AGVQEVKIRS ALTCELVNGI CGKCYGRDLA
910 920 930 940 950 960
RGTPVNHGEA VGVIAAQSIG EPGTQLTMRT FHIGGAAQIN EQSVIESNFE GKVVIKNKAI
970 980 990 1000 1010 1020
ARNGENHSVA MVRNMVVAIV DPDGTERATH RIQYGARMHV DEGDTVKRGQ RIAEWDPYSR
1030 1040 1050 1060 1070 1080
PVLTEVEGTI DFEDLVEDQS ISETLDESTG IAKRIVIDWR STRGGADLRP AIVVKGKDGK
1090 1100 1110 1120 1130 1140
VLKLARGGDA RYMLSVDAIL SVDVGAKVKP GDILARISTE SAKTRDITGG LPRVAELFEA
1150 1160 1170 1180 1190 1200
RKPKDAAIIA EIAGTIRFGR DYKNKRRISI EPMDSEEEAR EYLIPKGKHI HLQDGDIVEK
1210 1220 1230 1240 1250 1260
GDFIVEGNPA PHDILAIKGI EELAAYLVNE IQEVYRLQGV LINDKHIEVI VRQMLQKVEI
1270 1280 1290 1300 1310 1320
TDQGETDMIS GEQIDKIEFD QLNAKARDEG KKIATGTPVL LGITKASLQT RSFFSAASFQ
1330 1340 1350 1360 1370 1380
ETTRVLTEAA VNGKVDPLEG LKENVIVGRL IPAGTGASMA KLREVAMKRD RMILDEREKQ
1390
ATIVPPAAPE AEPLALPPVE