Q2IFT1
Gene name |
pckG |
Protein name |
Phosphoenolpyruvate carboxykinase [GTP] |
Names |
PEP carboxykinase, PEPCK |
Species |
Anaeromyxobacter dehalogenans (strain 2CP-C) |
KEGG Pathway |
ade:Adeh_3676 |
EC number |
4.1.1.32: Carboxy-lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2IFT1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2IFT1-F1 | Predicted | AlphaFoldDB |
No variants for Q2IFT1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2IFT1 | |||||
No associated diseases with Q2IFT1
3 regional properties for Q2IFT1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site | 254 - 262 | IPR018091 |
| domain | Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain | 230 - 583 | IPR035077 |
| domain | Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal | 18 - 226 | IPR035078 |
Functions
| Description | ||
|---|---|---|
| EC Number | 4.1.1.32 | Carboxy-lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| manganese ion binding | Binding to a manganese ion (Mn). |
| phosphoenolpyruvate carboxykinase (GTP) activity | Catalysis of the reaction: GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO2. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| gluconeogenesis | The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSTSPAARPT | SNPHLLGWVD | EMAKLCKPDR | VHWCDGSEAE | KKRLTDDAVA | AKVLIPLDQQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KWPGCHYHHS | NPSDVARVEH | LTFICTPTKE | QAGPTNNWME | PKEAYRKLGA | IFDGSMKGRT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MYVVPYVMGP | STSPFAKVGI | EITDSVYVAL | NMGIMARMGK | VALDRLGDSN | EFNRGLHSVA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DCNPERRFIC | HFPQDNTIWS | VGSGYGGNAL | LGKKCLALRI | ASYLAKNEGW | LAEHMLILEA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ESPTGEKQYV | AAAFPSACGK | TNFAMMIPPA | AFPGWKIRTV | GDDISWMRVG | EDGRLWAVNP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ENGYFGVAPG | TNRKTNPNAM | DSVRKDTIFT | NVARTPDGDI | WWEGMDHEAP | AELIDWKGQP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| WKKGSTEKAA | HPNSRFTAPA | KNNPAISPLV | DDPKGVPISA | IIFGGRRSTT | VPLVLEAFNW |
| 430 | 440 | 450 | 460 | 470 | 480 |
| THGVYLGSTM | GSETTAAATG | QVGVVRRDPM | AMLPFIGYDC | GSYLQHWLDM | QSRIPNPPKI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| FLVNWFRKSA | EGKFLWPGYG | DNMRVLKWML | DRAAGRAPAK | ETLLGYTPGD | AGLDLHGLDV |
| 550 | 560 | 570 | 580 | 590 | |
| SKDAIAAATR | IDLGEWEQEL | ESQAEWFEKL | GKTLPAPLAL | QRELLLERVR | AARKVK |