Q2I3G4

PR
Gene name
MT-ND5 (MTND5, NADH5, ND5)
Protein name
NADH-ubiquinone oxidoreductase chain 5
Names
NADH dehydrogenase subunit 5
Species
Elephas maximus (Indian elephant)
KEGG Pathway
EC number
7.1.1.2: Hydron translocation or charge separation linked to oxidoreductase reactions
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

478-606 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2I3G4

Entry ID Method Resolution Chain Position Source
AF-Q2I3G4-F1 Predicted AlphaFoldDB

No variants for Q2I3G4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2I3G4

No associated diseases with Q2I3G4

No regional properties for Q2I3G4

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q2I3G4

Functions

Description
EC Number 7.1.1.2 Hydron translocation or charge separation linked to oxidoreductase reactions
Subcellular Localization
  • Mitochondrion inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
respirasome The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.

1 GO annotations of molecular function

Name Definition
NADH dehydrogenase (ubiquinone) activity Catalysis of the reaction: NADH + ubiquinone + 5 H(+)(in) <=> NAD(+) + ubiquinol + 4 H(+)(out).

2 GO annotations of biological process

Name Definition
mitochondrial electron transport, NADH to ubiquinone The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation.
mitochondrial respiratory chain complex I assembly The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKVINLIPTL TLTSLIILTL PITMTLLQNN KTNCFLYITK MAVTCAFAIS LIPTLLFLQS
70 80 90 100 110 120
NQEAYISNWH WMTIQTLKLS LSFKLDFFSL TFMPIALFIT WSIMEFSLWY MHSDPHINRF
130 140 150 160 170 180
FKYLLLFLIT MLILVSANNL LQLFMGWEGV GIMSFLLISW WHGRTDANTA ALQAMLYNRI
190 200 210 220 230 240
GDMGFIMMMA WFIIHLNSWE FQQIFLTNPK NTTLPLLGLL LASAGKSAQF GLHPWLPSAM
250 260 270 280 290 300
EGPTPVSALL HSSTMVMAGV FTLIRFYPLM ENNLTIQTST LCLGAITTLF TAICALTQND
310 320 330 340 350 360
IKKIIALSTS SQLGLMMVTI GINQPHLAFT HMCTHAFFKA MLFLSSGSII HNLDNEQDIR
370 380 390 400 410 420
KMGGLYKTMP ITSTAIIIGS LALTGMPFLT GFYSKDPIIE TANMSYINTW ALLITLIAVS
430 440 450 460 470 480
MTASYSTRII FFALLGQPRY PTLIQVNENN PYLINPIKRL ILGSIFMGFF ISMNTIPHTT
490 500 510 520 530 540
PQMTMPPHLK FMALAVTLLG FTVATELNNM THNLTFKQPS RMHTFSTTLG YYPTTTHRIL
550 560 570 580 590 600
PYLSLTMSQN LATTIMDSIW LEKMIPKNLT TMQKTAASLV SNQKGLMKLY FLSFLLSITL
GLLITL