Q2H683

PR
Gene name
UTR4
Protein name
Enolase-phosphatase E1
Names
2,3-diketo-5-methylthio-1-phosphopentane phosphatase
Species
Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) (Soil fungus)
KEGG Pathway
EC number
3.1.3.77: Phosphoric monoester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

120-203 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2H683

Entry ID Method Resolution Chain Position Source
AF-Q2H683-F1 Predicted AlphaFoldDB

No variants for Q2H683

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2H683

No associated diseases with Q2H683

No regional properties for Q2H683

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q2H683

Functions

Description
EC Number 3.1.3.77 Phosphoric monoester hydrolases
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity Catalysis of the reaction: 2,3-diketo-5-methylthiopentyl-1-phosphate = H+ + 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate. 2,3-diketo-5-methylthiopentyl-1-phosphate is also known as DK-MTP-1-P, and 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate as HK-MTPenyl-1-P.
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity Catalysis of the reaction: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate is also known as HK-MTPenyl-P, and 1,2-dihydroxy-3-keto-5-methylthiopentene as DHK-MTPene.
acireductone synthase activity Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate.
magnesium ion binding Binding to a magnesium (Mg) ion.

2 GO annotations of biological process

Name Definition
L-methionine salvage from methylthioadenosine The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine.
L-methionine salvage from S-adenosylmethionine The chemical reactions and pathways resulting in the formation of L-methionine from S-adenosylmethionine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAAAKKPRVV LLDIEGTVCP ISFVKDVLFP YALSALPSTL AQEWDAPAFA RYRAAFPAEH
70 80 90 100 110 120
ASTPSALAAH ARDLMARDVK IGYLKALQGY LWEAGYASGA LRAPLFEDVA PKVREWTSAA
130 140 150 160 170 180
GEEGGVARVM IYSSGSVPAQ KLLFRHTSGE PADLTDAITD YFDTVNAGPK TEPASYERIA
190 200 210 220 230
AKYPEVPAGE WLFLSDNVRE VEAAREAGMR ACVVQRPGNA ELPEDVRGRL EVVESFEEL