Q2GLF7

PR
Gene name
gmk
Protein name
Guanylate kinase
Names
GMP kinase
Species
Anaplasma phagocytophilum (strain HZ)
KEGG Pathway
aph:APH_0170
EC number
2.7.4.8: Phosphotransferases with a phosphate group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-78 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for Q2GLF7

Entry ID Method Resolution Chain Position Source
3LNC X-ray 195 A A/B 1-210 PDB
AF-Q2GLF7-F1 Predicted AlphaFoldDB

No variants for Q2GLF7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2GLF7

No associated diseases with Q2GLF7

3 regional properties for Q2GLF7

Type Name Position InterPro Accession
domain Guanylate kinase-like domain 6 - 186 IPR008144
domain Guanylate kinase/L-type calcium channel beta subunit 5 - 189 IPR008145
conserved_site Guanylate kinase, conserved site 41 - 58 IPR020590

Functions

Description
EC Number 2.7.4.8 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
guanylate kinase activity Catalysis of the reaction: ATP + GMP = ADP + GDP.

1 GO annotations of biological process

Name Definition
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLKSVGVILV LSSPSGCGKT TVANKLLEKQ KNNIVKSVSV TTRAARKGEK EGKDYYFVDR
70 80 90 100 110 120
EEFLRLCSNG EIIEHAEVFG NFYGVPRKNL EDNVDKGVST LLVIDWQGAF KFMEMMREHV
130 140 150 160 170 180
VSIFIMPPSM EELRRRLCGR RADDSEVVEA RLKGAAFEIS HCEAYDYVIV NEDIEETADR
190 200
ISNILRAEQM KTCRQVGLRE LLESRFPIED