Q2GGQ8
Gene name |
infB |
Protein name |
Translation initiation factor IF-2 |
Names |
|
Species |
Ehrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas) |
KEGG Pathway |
ech:ECH_0563 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2GGQ8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2GGQ8-F1 | Predicted | AlphaFoldDB |
No variants for Q2GGQ8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2GGQ8 | |||||
No associated diseases with Q2GGQ8
5 regional properties for Q2GGQ8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translational (tr)-type GTP-binding domain | 340 - 510 | IPR000795 |
| domain | Small GTP-binding protein domain | 344 - 496 | IPR005225 |
| domain | Translation initiation factor IF-2, N-terminal | 264 - 315 | IPR006847 |
| domain | Translation initiation factor IF- 2, domain 3 | 636 - 730 | IPR023115 |
| domain | Translation initiation factor IF-2, domain II | 516 - 612 | IPR044145 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| translation initiation factor activity | Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNESKSVVDS | GLMSGKIERT | TLKLSDKLKL | SSNIHQGTKF | SLKKSVTTVE | VRKSKKRKDI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NNIEQASVVL | QNDNAYQDNE | SNNSLTIQEQ | ISRMNALQNA | NICEKKEDIK | EDTSDVNLQV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TESTSVEKSE | SDDVTLEEES | SKKVEEQVVE | EAHDNTDTVS | LNVVENVQEE | SQVDNQVESS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NISDILQPKG | IEEKKLKKYE | KEHEEKKGNP | KKGVSNNMYS | KHVKLVIEEE | LEDNNKQVIQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| THKSRKNRST | SSVKNKITRK | VLIPKKITVQ | ELASSMSERV | KDVQHMLFQM | GRRDIKPTDF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LDSDHASVIV | EAFNHTFKLV | NDGKLEEDLY | ADGNDKELLP | RAPVVTVMGH | VDHGKTSLLD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AIRKSNVADG | EFKGITQHIG | AYQIMLDGDK | RITFIDTPGH | EAFTAMRACG | TNVTDIVVLV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VAADDGIMPQ | TIESINHVKA | ANVAMIVAVN | KIDKHDANID | KITNSLLNHG | VVAESLGGDV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| IVVPVSAKER | INLDQLKSSI | LLMAELLELK | AVYDTRASGV | VIESKVDRNC | GVVATLIVQK |
| 550 | 560 | 570 | 580 | 590 | 600 |
| GTLKAGDIIV | VGHNSYGKVR | NMFNSDGRSE | KVAIPSMPVK | VLGLNNVPNS | GTNFIVVDSE |
| 610 | 620 | 630 | 640 | 650 | 660 |
| KQARELISYR | QELFNAELEA | NAKPKMDANS | ILACGVVDEL | NVILKCDVMG | SVEAICYSIS |
| 670 | 680 | 690 | 700 | 710 | 720 |
| KITHEDIKLN | VLYKGVGNVT | KSDVLLAETS | NSIILAFNVK | TDASVKELAK | QKCIEIKHYS |
| 730 | 740 | 750 | 760 | 770 | 780 |
| VIYDIIDDVK | KILSSMLKPL | QQEVQVGTLS | IRKVFSSGSI | GSVLGCYVTN | GIVRKGALVK |
| 790 | 800 | 810 | 820 | 830 | 840 |
| LIRNNNVIHE | GKIKVLRRFK | DDVKEVAAGF | ECGILLDYSK | EIYPESDIIH | ILEIVEEIRV |
| IK |