Q2GF50

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Ehrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas)
KEGG Pathway
ech:ECH_1149
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

798-862 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2GF50

Entry ID Method Resolution Chain Position Source
AF-Q2GF50-F1 Predicted AlphaFoldDB

No variants for Q2GF50

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2GF50

No associated diseases with Q2GF50

9 regional properties for Q2GF50

Type Name Position InterPro Accession
domain Helicase, C-terminal 424 - 628 IPR001650
conserved_site SEC-C motif 844 - 861 IPR004027
domain SecA DEAD-like, N-terminal 5 - 389 IPR011115
domain SecA Wing/Scaffold 610 - 820 IPR011116
domain SecA, preprotein cross-linking domain 227 - 345 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 88 - 246 IPR014001
domain SecA motor DEAD 2 - 612 IPR014018
conserved_site SecA conserved site 487 - 502 IPR020937
domain SecA, C-terminal helicase domain 407 - 582 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLSIAHKIFG STNSRIIKSF HKVVQDINAI EHEIQLLSNE ALKHKTIEFK EELKNGKTLD
70 80 90 100 110 120
DILVPAFAVV REASKRVLNM RHFDVQLIGG IVLHKGMISE MKTGEGKTLV ATLAAYLNAL
130 140 150 160 170 180
EGKGVHIVTV NDYLAKRDAE WMGELYSALG ITVGCILTET NDLERKNAYN CDILYSTNNN
190 200 210 220 230 240
LGFDYLRDNM KFSRDEMVQR GFNYAIVDEV DSILIDEART PLIISGQVDQ DIKMYKKIDN
250 260 270 280 290 300
LIYELAEEDY ELEEKNRNIF LTEAGITKIE NLLIQHNLIS SNTSLYDIDN IIIMHYITQA
310 320 330 340 350 360
LRAHKMFAVD KDYIIKDGNI VIIDEFTGRM MDGRRYSDGL HQALEAKEKL NINSENQTLA
370 380 390 400 410 420
STTFQNYFRM YTKLSGMTGT AETESEEFLG IYNLQVVQIP TNIPVQRIDL NDDIYCTEEE
430 440 450 460 470 480
KFNSVIKFIS ECHKKLQPVL VGTVSIEKSE MLSKLLTKNK LKHSVLNARY HEQEAYIIAQ
490 500 510 520 530 540
AGIPGTITIA TNMAGRGTDI QLGGNLKMLA KTALANITDK EAIEIKYKQL TEKVNRDKEI
550 560 570 580 590 600
AIQAGGLCVI GTERHESRRI DNQLRGRSGR QGDPGLSKFF LSLEDDLLRI FGSDKIKGVL
610 620 630 640 650 660
QKLGMKKDEA IQHTWISRSI EKAQHKVESR NYDIRKSLLK FDNVINEQRK VVFDQRNKIL
670 680 690 700 710 720
DSDSYDISII YRDLNSDIVN SIIHDKYYNL DDDTYKALSS EFTRIYNITL DYSTISNFES
730 740 750 760 770 780
KDKVLEHLNE TVDEHFAQKI EEFTLKDQKA WDHVVKKVMI MSLDYLWRDH LAALDSLKCG
790 800 810 820 830 840
INLRSIAQKD PLNEFKAEAF SMLENMMSKF YELIIQRLSH LKFDIELNDT QRIEYNIHHS
850 860
KISRNEKCPC GSGKKFKHCH GA