Q2GEH0

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Neorickettsia sennetsu (strain ATCC VR-367 / Miyayama) (Ehrlichia sennetsu)
KEGG Pathway
nse:NSE_0232
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-83 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2GEH0

Entry ID Method Resolution Chain Position Source
AF-Q2GEH0-F1 Predicted AlphaFoldDB

No variants for Q2GEH0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2GEH0

No associated diseases with Q2GEH0

8 regional properties for Q2GEH0

Type Name Position InterPro Accession
domain Helicase, C-terminal 410 - 614 IPR001650
domain SecA DEAD-like, N-terminal 5 - 390 IPR011115
domain SecA Wing/Scaffold 596 - 793 IPR011116
domain SecA, preprotein cross-linking domain 228 - 346 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 89 - 247 IPR014001
domain SecA motor DEAD 2 - 599 IPR014018
conserved_site SecA conserved site 488 - 503 IPR020937
domain SecA, C-terminal helicase domain 408 - 569 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLDLVHKIFD SRNRKIKRKL KDGLEQVNSL ETRIRDLSSD ELRNKTSEFK ERLFKQSASL
70 80 90 100 110 120
DEILPEAYAC VREASLRTLG MRHFDVQIMG GIVLHWGMIS EMHTGEGKTL VATLAAYLNA
130 140 150 160 170 180
LSEKGVHVVT VNDYLARRDT EWMKQIYRHL GLQVSCITSD MRDPERAHAY KADITYATNN
190 200 210 220 230 240
ELGFDYLRDN MKFSKGEMVQ RDLHYAIVDE VDSILIDEAR TPLIISGVTD NASYLYASMN
250 260 270 280 290 300
KLAEKLDSTL YIVDEKTRTV SLTEEGQEAI EKLLMAEKFI ESGSSLYEPQ NLQLVHCLNQ
310 320 330 340 350 360
SLKAINLFQK NKDYIVQDGQ IVLIDEFTGR MMHGRRYSEG LHQALEAKEN LKIQNENQTL
370 380 390 400 410 420
ASITFQNYFR MYGKLSGMTG TAATEREEFS TIYGLEVVQI PSHLPVRRVD HDDEIYASKK
430 440 450 460 470 480
EKYEAILALA KECHEKLQPI LIGTTSIENS EELSRELKKA KLKHSVLNAK QHAFEAEIIA
490 500 510 520 530 540
QAGKPGAITI ATNMAGRGTD IQLGGNINFN ISANDEAEKE HAKNEEIVRK AGGLYVIGTE
550 560 570 580 590 600
RHESRRIDNQ LRGRSGRQGD PGESKFFLSL DDDLLRVFGT SGIRNMLKKQ LSNNGAIKHS
610 620 630 640 650 660
YITRSLEKAQ KKVESRNYEI RKNLIKFDDV INEQRKVIFS QRNNIMESGD IDLLPIVTEV
670 680 690 700 710 720
NAKTLENARS KNFYDISTLI HSMQSIYNED FKELHKTEDI DGFIDSKTKS IIAEKERAHV
730 740 750 760 770 780
EFLLEIKKRI MIAILDQLWK EHLQFLENLR LSINLKAVAQ KNPLIEFKHE AFQAFQRLSE
790 800
RWHENIIASF VRVKLVERMH MKVM