Q2G5E7

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 / F199)
KEGG Pathway
nar:Saro_2490
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-315 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2G5E7

Entry ID Method Resolution Chain Position Source
AF-Q2G5E7-F1 Predicted AlphaFoldDB

No variants for Q2G5E7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2G5E7

No associated diseases with Q2G5E7

6 regional properties for Q2G5E7

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 374 - 544 IPR000795
domain Small GTP-binding protein domain 377 - 534 IPR005225
domain Translation initiation factor IF-2, N-terminal 299 - 348 IPR006847
domain Initiation factor 2 associated domain, bacterial 13 - 48 IPR013575
domain Translation initiation factor IF- 2, domain 3 650 - 764 IPR023115
domain Translation initiation factor IF-2, domain II 551 - 645 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDSDKKPTL GRRPLGLKTA VEAGEVKQTF SHGRTNKVVV EVKRRKLMGR PGEAAPTAAP
70 80 90 100 110 120
AAAATPAPTP VAPPPPPPPP PPPPSASRET RQEMQVRLLR EAEEARLAAL EAANRREQEE
130 140 150 160 170 180
RLRAIEEERR RAEEKARAEA EAAAAPAAPA APAAPSAAPA AAQSAPEAAP APVAEPEVAR
190 200 210 220 230 240
QPEAAPVAAT APAAPKAEEA KPAAPAVPAP RRFTPVAPAA PIKRPELAAK KPAHPQRDRK
250 260 270 280 290 300
TEDRRGGKLT VTRALNEDEG ARARSLAALK RAREKERRAH FAGQSQPREK QVRDVVVPDA
310 320 330 340 350 360
ITVQDLANRM AEKAADLVKA LFKMGMMVTI NQTIDQDTAE LLVTEFGHNI QRVSESDADI
370 380 390 400 410 420
DTSADVDPEE SLKARPPVVT IMGHVDHGKT SLLDALRGTD VVRGEAGGIT QHIGAYQIKT
430 440 450 460 470 480
KGGDFITFLD TPGHEAFTEM RIRGANVTDI VILVVAGDDG LMPQTIEAIN HTKAAGVPMI
490 500 510 520 530 540
VAITKADKPE FQPQKIRERL LEHEIIVEAM SGDVQDVEVS AKTGAGLDEL IEKILLQAEL
550 560 570 580 590 600
LELKANPDRS AEATVIEAKL DKGKGPLATV LVNRGTLKVG DILVVGTQSG RVRAMLDDKG
610 620 630 640 650 660
RQVKAAGPSL PVEVLGIGGV PMAGDTLTVV ESEARAREVA AYRQERATAK RTAQAPASLE
670 680 690 700 710 720
NMFSALAAKN AVIEYPLVIR ADVQGSAEAI VNALNKISTD EIKVRILASG VGAITESDVN
730 740 750 760 770 780
LAQASGAPIV GFNVRPNAKA RELIERNKVR MKYFDVIYQL TDDIRSEMAG ELGPEAIETV
790 800 810 820 830 840
VGRAEVKEVF PAGKRDKAAG LLVVEGVIRK GLHARLTRND VIVSRTTIAS LRRFKDDVPE
850 860 870
VRAGLECGVL LQDTNDIKAG DQLEVFEVEM RERTL