Q2FY15

PR
Gene name
cshB
Protein name
DEAD-box ATP-dependent RNA helicase CshB
Names
Species
Staphylococcus aureus (strain NCTC 8325 / PS 47)
KEGG Pathway
sao:SAOUHSC_01659
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

341-448 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q2FY15

Entry ID Method Resolution Chain Position Source
AF-Q2FY15-F1 Predicted AlphaFoldDB

No variants for Q2FY15

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q2FY15

No associated diseases with Q2FY15

4 regional properties for Q2FY15

Type Name Position InterPro Accession
domain Helicase, C-terminal 232 - 386 IPR001650
domain DEAD/DEAH box helicase domain 28 - 192 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 23 - 221 IPR014001
domain RNA helicase, DEAD-box type, Q motif 4 - 32 IPR014014

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

5 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.
RNA strand annealing activity An activity that facilitates the formation of a complementary double-stranded RNA molecule.

3 GO annotations of biological process

Name Definition
response to cold Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
ribosomal large subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.
RNA catabolic process The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKHPFEQFN LESSLIDAVK DLNFEKPTEI QNRIIPRILK RTNLIGQSQT GTGKSHAFLL
70 80 90 100 110 120
PLMQLIDSEI KEPQAIVVAP TRELAQQLYD AANHLSQFKA GVSVKVFIGG TDIEKDRQRC
130 140 150 160 170 180
NAQPQLIIGT PTRINDLAKT GHLHVHLASY LVIDEADLMI DLGLIEDVDY IAARLEDNAN
190 200 210 220 230 240
IAVFSATIPQ QLQPFLNKYL SHPEYVAVDS KKQNKKNIEF YLIPTKGAAK VEKTLNLIDI
250 260 270 280 290 300
LNPYLCIIFC NSRDNANDLA RSLNEAGIKV GMIHGGLTPR ERKQQMKRIR NLEFQYVIAS
310 320 330 340 350 360
DLASRGIDIE GVSHVINFDV PNDIDFFTHR VGRTGRGNYK GVAITLYSPD EEHNISLIED
370 380 390 400 410 420
RGFVFNTVDI KDGELKEVKA HNQRQARMRK DDHLTNQVKN KVRSKIKNKV KPGYKKKFKQ
430 440
EVEKMKRQER KQFSKQQNRQ KRKQNKKG