Q2FSK9
Gene name |
nadX |
Protein name |
L-aspartate dehydrogenase |
Names |
|
Species |
Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1) |
KEGG Pathway |
mhu:Mhun_2354 |
EC number |
1.4.1.21: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2FSK9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2FSK9-F1 | Predicted | AlphaFoldDB |
No variants for Q2FSK9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2FSK9 | |||||
No associated diseases with Q2FSK9
Functions
| Description | ||
|---|---|---|
| EC Number | 1.4.1.21 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| aspartate dehydrogenase activity | Catalysis of the reaction: L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H + H+. |
| NAD binding | Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH. |
| NADP binding | Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH. |
| oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor | Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| NAD biosynthetic process | The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVRIGLLGCG | NVGRIIATHQ | DGFTVEALFD | RLPDHAEELA | RMCGAPAYAD | FQEFISQDFD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ICVEAASVLA | VREYAPKILE | NGKHVLILSV | GALSDTNFRK | ILLDVARSQG | KKIHIPSGAI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MGLDNLKVGG | ISRIDSVLLR | TTKSPASLGM | QVSHRTLAFR | GKANECIKQF | PKNINVSVAL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ALAVHHDVDV | ELWADPEVDR | NIHDIFVSGE | FGEASIRVVN | HPSPDNPATS | YLAALSVLSL |
| 250 | |||||
| LKNLDSPLVI | GS |