Q2FK44
Gene name |
pflB (SAUSA300_0220) |
Protein name |
Formate acetyltransferase |
Names |
Pyruvate formate-lyase |
Species |
Staphylococcus aureus (strain USA300) |
KEGG Pathway |
saa:SAUSA300_0220 |
EC number |
2.3.1.54: Transferring groups other than amino-acyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q2FK44
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q2FK44-F1 | Predicted | AlphaFoldDB |
No variants for Q2FK44
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q2FK44 | |||||
No associated diseases with Q2FK44
1 regional properties for Q2FK44
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Phosphofructokinase domain | 3 - 275 | IPR000023 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.1.54 | Transferring groups other than amino-acyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| formate C-acetyltransferase activity | Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| glucose metabolic process | The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLETNKNHAT | AWQGFKNGRW | NRHVDVREFI | QLNYTLYEGN | DSFLAGPTEA | TSKLWEQVMQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LSKEERERGG | MWDMDTKVAS | TITSHDAGYL | DKDLETIVGV | QTEKPFKRSM | QPFGGIRMAK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AACEAYGYEL | DEETEKIFTD | YRKTHNQGVF | DAYSREMLNC | RKAGVITGLP | DAYGRGRIIG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DYRRVALYGV | DFLMEEKMHD | FNTMSTEMSE | DVIRLREELS | EQYRALKELK | ELGQKYGFDL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SRPAENFKEA | VQWLYLAYLA | AIKEQNGAAM | SLGRTSTFLD | IYAERDLKAG | VITESEVQEI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IDHFIMKLRI | VKFARTPDYN | ELFSGDPTWV | TESIGGVGID | GRPLVTKNSF | RFLHSLDNLG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PAPEPNLTVL | WSVRLPDNFK | TYCAKMSIKT | SSIQYENDDI | MRESYGDDYG | IACCVSAMTI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GKQMQFFGAR | ANLAKTLLYA | INGGKDEKSG | AQVGPNFEGI | NSEVLEYDEV | FKKFDQMMDW |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LAGVYINSLN | VIHYMHDKYS | YERIEMALHD | TEIVRTMATG | IAGLSVAADS | LSAIKYAQVK |
| 550 | 560 | 570 | 580 | 590 | 600 |
| PIRNEEGLVV | DFEIEGDFPK | YGNNDDRVDD | IAVDLVERFM | TKLRSHKTYR | DSEHTMSVLT |
| 610 | 620 | 630 | 640 | 650 | 660 |
| ITSNVVYGKK | TGNTPDGRKA | GEPFAPGANP | MHGRDQKGAL | SSLSSVAKIP | YDCCKDGISN |
| 670 | 680 | 690 | 700 | 710 | 720 |
| TFSIVPKSLG | KEPEDQNRNL | TSMLDGYAMQ | CGHHLNINVF | NRETLIDAME | HPEEYPQLTI |
| 730 | 740 | ||||
| RVSGYAVNFI | KLTREQQLDV | ISRTFHESM |