Q295E6

PR
Gene name
GA22038
Protein name
ATP-dependent RNA helicase SUV3 homolog, mitochondrial
Names
Species
Drosophila pseudoobscura pseudoobscura (Fruit fly)
KEGG Pathway
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

636-762 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q295E6

Entry ID Method Resolution Chain Position Source
AF-Q295E6-F1 Predicted AlphaFoldDB

No variants for Q295E6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q295E6

No associated diseases with Q295E6

4 regional properties for Q295E6

Type Name Position InterPro Accession
domain Helicase, C-terminal 331 - 508 IPR001650
domain Suv3, C-terminal domain 1 545 - 586 IPR041082
domain Suv3, N-terminal 52 - 166 IPR041453
domain Suv3, DEXQ-box helicase domain 187 - 332 IPR044774

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Mitochondrion
  • Unlike in mammals, does not localize to the nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.

5 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA helicase activity Unwinding of a DNA helix, driven by ATP hydrolysis.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
DNA duplex unwinding The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQNTRRCISL ICVTRQPPSL RATYGAVAAA RCLHRAPPQS SRKKHETNVS TLFKPVQVQA
70 80 90 100 110 120
NVDCEDVGSE LVGKLEKSEL LKILNKFTQR RETKSLCSEN GLDSYLQQQA FGSFRRYCIE
130 140 150 160 170 180
AENLPVDLHI IFSDIMQGAG HIDDIFPYFL RHAKTVFPHL DCMDDLKKIS DLRQPANWYT
190 200 210 220 230 240
NARALTRKIV FHSGPTNSGK TYHAMERYLS AKTGVYCGPL KLLATEVYNK ANERGTPCDL
250 260 270 280 290 300
VTGEERKFGI SDNSPANHVA CTVEMTSVNT PYEVAVIDEI QQIRDPQRGW AWTRAFLGLI
310 320 330 340 350 360
ADEVHVCGEA GALELLQKIC ETTGETVEVR RYDRLTELTV EDSALGSLDN VMPGDCIVCF
370 380 390 400 410 420
SKHDIYTVSR EIEARGKEVA VIYGGLPPGT KLAQAAKFND PANSCKVMVA TDAIGMGLNL
430 440 450 460 470 480
SIRRIIFYSL VKPTMNERGE REIDTISVSS ALQIAGRAGR FRTQWEHGYV TAFKSEDLQT
490 500 510 520 530 540
LQRILAQTPE PLKQAGLHPT ADQIELYAYH LPNSSLSNLM DIFVNLCTVD DSLYFMCNIE
550 560 570 580 590 600
DFKFLAEMIQ HVPLPLRARY VFCCAPINRK MPFVCSMFLK IARQYSRNEP ITFEFIKSNC
610 620 630 640 650 660
GWPFKLPKTI LDLVHLESVF DVMDLYRFMD LFPEAGNVRE AQKELDEIIQ QGVFQITRLL
670 680 690 700 710 720
KNTEASQEGE TPNYSMRRVT HVKEPRLPSA SRGRLTDRLL AQGLLTPGML SELRKEWDAQ
730 740 750 760
QVGQAAAAST SSKESQESPP DDSDDEDSYP GSYKKTRRKR RK