Q292F0
Gene name |
Tango7 |
Protein name |
Eukaryotic translation initiation factor 3 subunit M |
Names |
eIF3m, Transport and Golgi organization protein 7, Tango-7 |
Species |
Drosophila pseudoobscura pseudoobscura (Fruit fly) |
KEGG Pathway |
dpo:Dpse_GA20974 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q292F0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q292F0-F1 | Predicted | AlphaFoldDB |
No variants for Q292F0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q292F0 | |||||
No associated diseases with Q292F0
6 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| eukaryotic 43S preinitiation complex | A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA. |
| eukaryotic 48S preinitiation complex | A protein complex composed of the small ribosomal subunit, eIF3, eIF1A, methionyl-initiatior methionine and a capped mRNA. The complex is initially positioned at the 5'-end of the capped mRNA. |
| eukaryotic translation initiation factor 3 complex, eIF3m | An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3m. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| investment cone | A cytoskeletal part that consists of a microfilament-rich cone that forms round each nucleus in a spermatogenic cyst and translocates the length of the cyst during sperm individualization. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| caspase binding | Binding to a caspase family protein. |
| translation initiation factor activity | Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| activation of cysteine-type endopeptidase activity | Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase. |
| formation of cytoplasmic translation initiation complex | Joining of the large subunit, with release of IF2/eIF2 and IF3/eIF3. This leaves the functional ribosome at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site. |
| Golgi organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. |
| positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis | Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis. |
| protein secretion | The controlled release of proteins from a cell. |
| sperm individualization | The resolution of the male germline syncytium or cyst into individual gametes by packaging each spermatid into its own plasma membrane. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTSHPVFIDL | SLDEQVQELR | KYFKKLGAEI | SSEKSNKGVE | DDLHKIIGVC | DVCFKDGEPS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QIDGILNSIV | SIMITIPLDR | GENIVLAYCE | KMTKAPNQPL | GKVCLQSLWR | LFNNLDTASP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LRYHVYYHLV | QVAKQCEQVL | EVFTGVDQLK | TQFANCPPSS | EQMQKLYRLL | HDVTKDTNME |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LSSKVMIELL | GTYTADNACV | AREDAMKCIV | TALADPNTFL | LDPLLALKPV | RFLEGDLIHD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LLSIFVSDKL | PSYVQFYEDH | KEFVNSQGLN | HEQNMKKMRL | LTFMQLAESN | PEMTFDTLTK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ELQITEDEVE | PFVIQVLKTK | LVRARLDQAN | RKVHISSTMH | RTFGAPQWEQ | LRDLLQAWKE |
| 370 | 380 | ||||
| NLSSVRDGLT | NVSSAQLELA | RTQKLIH |