Q28VP7

PR
Gene name
ubiG
Protein name
Ubiquinone biosynthesis O-methyltransferase
Names
2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase
Species
Jannaschia sp (strain CCS1)
KEGG Pathway
jan:Jann_0298
EC number
2.1.1.64: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-48 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q28VP7

Entry ID Method Resolution Chain Position Source
AF-Q28VP7-F1 Predicted AlphaFoldDB

No variants for Q28VP7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q28VP7

No associated diseases with Q28VP7

3 regional properties for Q28VP7

Type Name Position InterPro Accession
repeat Mitochondrial substrate/solute carrier 6 - 97 IPR018108-1
repeat Mitochondrial substrate/solute carrier 101 - 190 IPR018108-2
repeat Mitochondrial substrate/solute carrier 197 - 288 IPR018108-3

Functions

Description
EC Number 2.1.1.64 Methyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
2-polyprenyl-6-hydroxyphenol methylase activity Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol.
2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity Catalysis of the reaction: 2-polyprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
3-demethylubiquinone-9 3-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9.

2 GO annotations of biological process

Name Definition
methylation The process in which a methyl group is covalently attached to a molecule.
ubiquinone biosynthetic process The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTAAPDATGT VNTVDAGEVA KFEAMAAEWW DLEGKFKPLH MLNPTRLDYI TQQIAAEFGR
70 80 90 100 110 120
DLKADAPFAG LHILDIGCGG GLLAEPMARL GADVVGADAA ERNIPVAQVH AAQSGLEIDY
130 140 150 160 170 180
RHTTAEAMAD AGEQFDVVLN MEVVEHVVDP LGYLTACQRL LKPGGLMVCS TLNRNPKSYL
190 200 210 220 230 240
MAIIGAEHVM RWLPKGTHEW SKFITPDELF DLIRQAGLDP VDRKGFVFNP LLWTWGISER
250
DMSVNYVTAS VKQV