Q28BZ7
Gene name |
cep57l1 (cep57, cep57r, TEgg135a06.1) |
Protein name |
Centrosomal protein cep57l1 |
Names |
Centrosomal protein 57kDa-like protein 1, Centrosomal protein of 57 kDa, Cep57, Cep57-related protein, Cep57R |
Species |
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) |
KEGG Pathway |
xtr:733970 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q28BZ7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q28BZ7-F1 | Predicted | AlphaFoldDB |
No variants for Q28BZ7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q28BZ7 | |||||
No associated diseases with Q28BZ7
No regional properties for Q28BZ7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q28BZ7 | |||
Functions
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| centrosome | A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| kinetochore | A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. |
| microtubule | Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. |
| spindle | The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| gamma-tubulin binding | Binding to the microtubule constituent protein gamma-tubulin. |
| identical protein binding | Binding to an identical protein or proteins. |
| microtubule binding | Binding to a microtubule, a filament composed of tubulin monomers. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MESLSKESYL | SSFHQFPSYA | PLPDHIKFES | VSSKKIQCSA | LENISPHQYD | ILQAPNSRAL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ISALKTLQEK | ICRLELEKTH | ARDRLTNLTR | VAGEHKKVLE | SEKQSAELAA | KEATNQQNDI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GKQLNNAKQR | CSLLEKQLDY | MKEMMENADT | QKTTIHEHQM | LTQKEQKEIQ | SKLKKLEVLE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KMCTRLSATH | KSAETKIQHL | EEKLSVEEQN | RKALQDKAAQ | VQTSLEVNRI | LLSSASAQNS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TQRKVKKKKQ | SKLKNSVSKE | PPSKCFYPKA | GELPFVAGKS | TTSSHSLSAN | VQNVLHMMKH |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HSPQVSQKNP | KTAEHKPSVL | PGGSRTIPTR | LISSFTGDNL | SDILLALQDE | LGQMSFEHQE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LLRHINETKN | TDMREDLERE | LDYVVKQMEI | KSDQIMKLKR | HQLNVNKLKK | TAKLLKEQPR |
| 430 | 440 | 450 | 460 | 470 | 480 |
| PTSVTKLAAD | KQNTGAKDPS | TPRRKGDLAD | GSGTPNSKAS | LELLKSVRKI | QMTLKKDDIM |
| WEK |