Q28616

PR
Gene name
AMHR2
Protein name
Anti-Muellerian hormone type-2 receptor
Names
Anti-Muellerian hormone type II receptor, AMH type II receptor, MIS type II receptor, MISRII, MRII
Species
Oryctolagus cuniculus (Rabbit)
KEGG Pathway
ocu:100009599
EC number
2.7.11.30: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

486-569 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q28616

Entry ID Method Resolution Chain Position Source
AF-Q28616-F1 Predicted AlphaFoldDB

No variants for Q28616

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q28616

No associated diseases with Q28616

2 regional properties for Q28616

Type Name Position InterPro Accession
domain Glycosyltransferase 2-like 76 - 245 IPR001173
domain Dolichyl-phosphate beta-glucosyltransferase 77 - 302 IPR035518

Functions

Description
EC Number 2.7.11.30 Protein-serine/threonine kinases
Subcellular Localization
  • Membrane ; Single-pass type I membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
transmembrane receptor protein serine/threonine kinase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

1 GO annotations of biological process

Name Definition
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLGTLGLWAL LPAAVQAPPN RRTCVFFEAP GVRGSTKTLG ELLDAGPGPP RVIRCLYSRC
70 80 90 100 110 120
CFGIWNLTRD QAQVEMQGCR DSDEPGCESL SCDPSPRARA SSGSTLFTCS CGADFCNANY
130 140 150 160 170 180
SHLPPLGGPG TPGPQGPQAA PGESPWMALA LLGLVLLLLL LLGGIVVALL QRKAYRVQSG
190 200 210 220 230 240
PEPEPDSGRD CSEELPELPQ LCFSQVIREG GHAAVWAGQL QGELVAIKVF PRRAVAQFRA
250 260 270 280 290 300
ERALYELPGL QHNHVVRFIA AGQGGPGPLP SGPLLVLELH PKGSLCQYLS QHTSDWGSSL
310 320 330 340 350 360
RMALSLAQGL AFLHEERWQD GQYKPGIAHR DLSSQNVLIR EDGSCAIGDL GLALVLPGFA
370 380 390 400 410 420
QPRAWAPPQP RGPAAIMEAG TQRYMAPELL DKSLDLQDWG TALRRADVYS LALLLWEILS
430 440 450 460 470 480
RCPDLRPDGR PPPFQLAYEA ELGSAPTTCE LWALAVEERR RPDIPSSWCC FATDPGGLRE
490 500 510 520 530 540
LLEDCWDADP EARLTAECVQ QRLVALVHPQ EAQPCPEGRP HSHPEDWPPA PAPAPALLPG
550 560
SPQPGACHFG VQQGLCSRNP GAACASSDV