Q28008
Gene name |
CLEC3A (CLECSF1) |
Protein name |
C-type lectin domain family 3 member A |
Names |
C-type lectin superfamily member 1, Cartilage-derived C-type lectin |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:282415 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q28008
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q28008-F1 | Predicted | AlphaFoldDB |
25 variants for Q28008
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs132799486 | 18 | D>E | No | EVA | |
| rs467448729 | 18 | D>Y | No | EVA | |
| rs449612742 | 20 | T>A | No | EVA | |
| rs464822865 | 23 | H>P | No | EVA | |
| rs432641722 | 26 | K>T | No | EVA | |
| rs454390875 | 31 | K>Q | No | EVA | |
| rs472794326 | 32 | H>P | No | EVA | |
| rs436593601 | 32 | H>Q | No | EVA | |
| rs476723803 | 34 | K>E | No | EVA | |
| rs438716318 | 68 | C>G | No | EVA | |
| rs460290634 | 69 | L>F | No | EVA | |
| rs478656366 | 69 | L>H | No | EVA | |
| rs442430348 | 75 | H>Q | No | EVA | |
| rs521522725 | 82 | A>V | No | EVA | |
| rs517293760 | 85 | L>S | No | EVA | |
| rs477747838 | 92 | N>K | No | EVA | |
| rs448010669 | 100 | G>R | No | EVA | |
| rs526495006 | 108 | A>T | No | EVA | |
| rs466278222 | 109 | D>Y | No | EVA | |
| rs436598691 | 124 | G>W | No | EVA | |
| rs448565508 | 125 | V>G | No | EVA | |
| rs519069994 | 154 | W>* | No | EVA | |
| rs800912916 | 161 | G>S | No | EVA | |
| rs797482821 | 184 | H>D | No | EVA | |
| rs800074232 | 189 | Y>F | No | EVA |
No associated diseases with Q28008
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular space | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| carbohydrate binding | Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| ossification | The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P25031 | Reg3b | Regenerating islet-derived protein 3-beta | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAKNGLVIYI | LVITLLLDQT | SCHASKFKAR | KHSKRRVKEK | DGDLKTQVEK | LWREVNALKE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MQALQTVCLR | GTKFHKKCYL | AAEGLKHFHE | ANEDCISKGG | TLVVPRSADE | INALRDYGKR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SLPGVNDFWL | GINDMVAEGK | FVDINGLAIS | FLNWDQAQPN | GGKRENCALF | SQSAQGKWSD |
| 190 | |||||
| EACHSSKRYI | CEFTIPQ |