Q27883
Gene name |
smd-1 (samdc) |
Protein name |
S-adenosylmethionine decarboxylase proenzyme |
Names |
AdoMetDC, SAMDC |
Species |
Onchocerca volvulus |
KEGG Pathway |
|
EC number |
4.1.1.50: Carboxy-lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q27883
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q27883-F1 | Predicted | AlphaFoldDB |
No variants for Q27883
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q27883 | |||||
No associated diseases with Q27883
No regional properties for Q27883
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q27883 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 4.1.1.50 | Carboxy-lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| adenosylmethionine decarboxylase activity | Catalysis of the reaction: S-adenosyl-L-methionine + H(+) = S-adenosylmethioninamine + CO(2). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| spermidine biosynthetic process | The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane. |
| spermine biosynthetic process | The chemical reactions and pathways resulting in the formation of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSTSTLSDGS | LDEGTFAAED | VSGVIEDYFF | EGAEKLLEIW | FDKNQNGATS | LRNIPYSELV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SMLDIAQCRI | LHSKSNECMD | SYVLSESSMF | ISDFRIILKT | CGTTRLLHAI | ERILHIAKIY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| CNMDNVVSVF | YSRKNFMHPE | KQPYPHSSFE | TEVDYLEEHF | AGGSAYCIGP | QRQDRWFLYT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MVTPQAVFPF | PEHTLEILMN | GLPEDVLSTF | SPNVSKDGKD | CRMKSAINTI | LPPDIVVHEE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LFSPCGYSLN | GLIPHSDHYI | TIHVTPEPDF | SYVSFETNQH | TLNLCEQMLK | VLEIFKPSKF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LLTIFTNELS | NEGKKMQKNL | WDLKICGCRR | TNLQFLELPT | ETLIYVQFER | IKSAEQVTCK |
| EVFDR |