Q27536

PR
Gene name
ZK1058.3
Protein name
Probable galactose-1-phosphate uridylyltransferase
Names
Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_ZK1058.3
EC number
2.7.7.12: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

3-84 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q27536

Entry ID Method Resolution Chain Position Source
AF-Q27536-F1 Predicted AlphaFoldDB

No variants for Q27536

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q27536

No associated diseases with Q27536

3 regional properties for Q27536

Type Name Position InterPro Accession
domain Galactose-1-phosphate uridyl transferase, N-terminal 5 - 177 IPR005849
domain Galactose-1-phosphate uridyl transferase, C-terminal 185 - 350 IPR005850
active_site Galactose-1-phosphate uridyl transferase, class I His-active site 152 - 169 IPR019779

Functions

Description
EC Number 2.7.7.12 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
UDP-glucose:hexose-1-phosphate uridylyltransferase activity Catalysis of the reaction: alpha-D-galactose 1-phosphate + UDP-D-glucose = alpha-D-glucose 1-phosphate + UDP-D-galactose.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
galactose catabolic process via UDP-galactose The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKQNNFRRY NPLIDEWVIV AVNRINRPWQ GAKTEKSTTI STSSNTEQSI LNPLAPGGTR
70 80 90 100 110 120
SSGIANENYV STYVFDNDFP SFTEFEECAG KDENDDLFKQ HEVKGVCKVI CYHPNSQLTL
130 140 150 160 170 180
ATMDVKEVRV VIDIWNQQYL ELGPKYEWVQ IFENRGAVVG CSNMHPHGQL WASNYLPTLP
190 200 210 220 230 240
MKKHESQKKH FEKHGKVMLM DYLEQETLKK ERIIMRNEHW TWLVPYWAFW PYETMLLPNR
250 260 270 280 290 300
HVERFTDLGE VEKQSLSEIL RSLLIKYDNV FECSFPYMMG WSGAPTGSFL TENCSFWQLH
310 320 330 340 350
LSFFPPLLRS ATVPKFLAGY EVFAEKQRDL SPEIAAKTLS EIDEEHYSKK LQ