Q27452

PR
Gene name
Protein name
Phenoloxidase subunit 2
Names
PO 2, Tyrosinase 2
Species
Bombyx mori (Silk moth)
KEGG Pathway
bmor:693073
EC number
1.14.18.1: With another compound as one donor, and incorporation of one atom of oxygen
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

30-102 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q27452

Entry ID Method Resolution Chain Position Source
AF-Q27452-F1 Predicted AlphaFoldDB

No variants for Q27452

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q27452

No associated diseases with Q27452

4 regional properties for Q27452

Type Name Position InterPro Accession
domain Hemocyanin/hexamerin middle domain 152 - 413 IPR000896
domain Tyrosinase copper-binding domain 399 - 410 IPR002227
domain Hemocyanin, C-terminal 424 - 677 IPR005203
domain Hemocyanin, N-terminal 27 - 143 IPR005204

Functions

Description
EC Number 1.14.18.1 With another compound as one donor, and incorporation of one atom of oxygen
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
tyrosinase activity Catalysis of the reaction: L-tyrosine + O2 = L-DOPAquinone + H2O. This reaction can use both monophenols (such as tyrosine) and catechols (o-diphenols) as substrates.

2 GO annotations of biological process

Name Definition
defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
melanin biosynthetic process from tyrosine The chemical reactions and pathways resulting in the formation of melanin from other compounds, including tyrosine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADVFESLEL LFDRPNEPLI TPKGENNSVF QLTEQFLTED YANNGIELNN RFGDDASEKI
70 80 90 100 110 120
PLKNLSKLPE FKIATQLPKD AEFSLFLPKH QEMANELLGV LMDVPENELQ DLLSTCAFAR
130 140 150 160 170 180
VNLNPQLFNY CYSVALMHRR DTRKVRVKNF AEVFPSKFLD SQVFTQARET AAVIPPDVPR
190 200 210 220 230 240
IPIIIPRDYT ATDLEEEHRL AYWREDIGIN LHHYHWHLVY PFTANDLSIV AKDRRGELFF
250 260 270 280 290 300
YMHQQVIARF NCERLCNSLK RVKKFSNWRE PIPEAYFPKL DSLTSSRGWP PRQSGMQWQD
310 320 330 340 350 360
LNRAAEGLFV TIDEMERWRR NVEEAIATGT VRLPNGQTRP LDIDTLGNML ESSALSPNRE
370 380 390 400 410 420
LYGSIHNNGH SFTAYMHDPE HRYLEQFGVI ADEATTMRDP FFYRWHAYID DVFQKHKESA
430 440 450 460 470 480
YVRPYTRSEL ENPGVQVRSV SVETPGGQPN TLNTFWMLSD VNLSRGLDFS DNGPVYARFT
490 500 510 520 530 540
HLNYRHFSYR INVNNTGSSR RTTVRIFITP KFDERNVPWI FSDQRKMCIE MDRFVTVLNA
550 560 570 580 590 600
GENNIVRQST ESSITIPFEQ TFRDLSAQGN DPRRDELATF NYCGCGWPQH MLVPKGTEAG
610 620 630 640 650 660
MPFQLFVMLS NYDLDRIDQD DGKQLTCVEA SSFCGLKDKK YPDRRAMGFP FDRPSSSATS
670 680 690
LQDFILPNMG LQDITIQLQN VTEPNPRNPP MSV