Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q25414
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q25414-F1 | Predicted | AlphaFoldDB |
No variants for Q25414
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q25414 | |||||
No associated diseases with Q25414
1 regional properties for Q25414
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | GPCR, rhodopsin-like, 7TM | 112 - 485 | IPR017452 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| G protein-coupled receptor activity | Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MANFTFGDLA | LDVARMGGLA | STPSGLRSTG | LTTPGLSPTG | LVTSDFNDSY | GLTGQFINGS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HSSRSRDNAS | ANDTSATNMT | DDRYWSLTVY | SHEHLVLTSV | ILGLFVLCCI | IGNCFVIAAV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MLERSLHNVA | NYLILSLAVA | DLMVAVLVMP | LSVVSEISKV | WFLHSEVCDM | WISVDVLCCT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ASILHLVAIA | MDRYWAVTSI | DYIRRRSARR | ILLMIMVVWI | VALFISIPPL | FGWRDPNNDP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DKTGTCIISQ | DKGYTIFSTV | GAFYLPMLVM | MIIYIRIWLV | ARSRIRKDKF | QMTKARLKTE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ETTLVASPKT | EYSVVSDCNG | CNSPDSTTEK | KKRRAPFKSY | GCSPRPERKK | NRAKKLPENA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NGVNSNSSSS | ERLKQIQIET | AEAFANGCAE | EASIAMLERQ | CNNGKKISSN | DTPYSRTREK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LELKRERKAA | RTLAIITGAF | LICWLPFFII | ALIGPFVDPE | GIPPFARSFV | LWLGYFNSLL |
| 490 | 500 | ||||
| NPIIYTIFSP | EFRSAFQKIL | FGKYRRGHR |