Q24QH6

PR
Gene name
purH
Protein name
Bifunctional purine biosynthesis protein PurH
Names
Species
Desulfitobacterium hafniense (strain Y51)
KEGG Pathway
dsy:DSY3927
EC number
2.1.2.3: Hydroxymethyl-, formyl- and related transferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

165-244 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q24QH6

Entry ID Method Resolution Chain Position Source
AF-Q24QH6-F1 Predicted AlphaFoldDB

No variants for Q24QH6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q24QH6

No associated diseases with Q24QH6

1 regional properties for Q24QH6

Type Name Position InterPro Accession
domain Methylglyoxal synthase-like domain 1 - 144 IPR011607

Functions

Description
EC Number 2.1.2.3 Hydroxymethyl-, formyl- and related transferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
IMP cyclohydrolase activity Catalysis of the reaction: IMP + H2O = 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide.
phosphoribosylaminoimidazolecarboxamide formyltransferase activity Catalysis of the reaction: 10-formyltetrahydrofolate + 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide = tetrahydrofolate + 5'-phosphoribosyl-5-formamido-4-imidazolecarboxamide.

1 GO annotations of biological process

Name Definition
'de novo' IMP biosynthetic process The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNRRAVLSVS NKTGLVELAR GLVELGFDLI STGGTFKTLT EAGLPVRYVT EVTGFPEILD
70 80 90 100 110 120
GRVKTLHPRI HGGILARATA EHLQQLEDNG IGLIDLVVVN LYPFKETIAR PGVSFQEAIE
130 140 150 160 170 180
NIDIGGPSMV RAAAKNQERV SIVVNPERYP EVLQALREQG EISYDMRKRL AAEAFAHTAE
190 200 210 220 230 240
YDQCIAGYLT AALAEESVSS SSSPFPATIT LGGQKAQDLR YGENPAQKAA FYRGADAAGT
250 260 270 280 290 300
LAYGEQIQGK ELSYNNWMDM DAAWGIVQDF SEPACAIIKH TNPCGTALGK TALEAYEKAL
310 320 330 340 350 360
AADPVSAFGG IIAFNRTVDA ECAASLKAHF YEVIVAHEFS SDARAILQEK KNLRLVKVAQ
370 380 390 400 410 420
DGKPAHTPWK VRSIQGGFLI QEEDEGTTPI SAWEVVSKRQ PEPEELRELD FAWRVVKHVK
430 440 450 460 470 480
SNAIVLAKAG QTLGVGAGQM NRVGSVKIAL EQAGDKAQGA YLASDAFFPF PDSLEEAAKA
490 500 510
GVRAVVQPGG SVRDAEVIEA ADRLNLIMVF TNRRHFKH