Q24798
Gene name |
GRP78 |
Protein name |
Endoplasmic reticulum chaperone BiP |
Names |
78 kDa glucose-regulated protein homolog, GRP-78 homolog, Binding-immunoglobulin protein homolog, BiP |
Species |
Echinococcus granulosus (Hydatid tapeworm) |
KEGG Pathway |
|
EC number |
3.6.4.10: Acting on ATP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q24798
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q24798-F1 | Predicted | AlphaFoldDB |
No variants for Q24798
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q24798 | |||||
No associated diseases with Q24798
2 regional properties for Q24798
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | GTF2I-like repeat | 98 - 192 | IPR004212-1 |
| repeat | GTF2I-like repeat | 323 - 417 | IPR004212-2 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.4.10 | Acting on ATP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum lumen | The volume enclosed by the membranes of the endoplasmic reticulum. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| ATP-dependent protein folding chaperone | Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGLSTYVGIF | LLCILTLSRC | KSGKEEYGTV | IGIDLGTTYS | CVGVFKNGRV | EIIANDQGNR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ITPSYVAFSG | DGERLIGDAA | KNQLTSNPKN | TLFDAKRLIG | RDYHDKDVQG | DIKRYPFKVI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NKNNKPYMKV | QVGSEEKGFA | PEEVSAMVLS | KMKEIAEAYL | GTEVTHAVVT | VPAYFNDAQR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QATKDAGAIA | GLTVLRIINE | PTAAAIAYGL | EKKDTEKNIL | VFDLGGGTFD | VSLLTIDNGV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FEVVATSGDT | HLGGEDFDQR | LIDYFVKLYK | KKEGKDITKD | DRAVQKLRRE | VEKAKRTLST |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EHSTMIEIDN | LFEGKDFSEP | LTRARFEELN | NDLFRSTLKP | VMKVMEDSGL | KKEDIDDIVL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VGGSTRIPKI | QQLVKEFFNG | KEPIRGINPD | EAVAYGAAVQ | AGVISGVEDT | GDIVLLDVCP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LTMGIETVGG | VMTKLIPRNT | VIPTKKSQIF | STAADNQPTV | TIQVFEGERP | MTKDNHFLGK |
| 490 | 500 | 510 | 520 | 530 | 540 |
| FDLTGIPPAP | RGLPQIEVTF | EIDVNGILRV | SAEDKGTGKK | SNIVINKETN | RITPEEIERM |
| 550 | 560 | 570 | 580 | 590 | 600 |
| IQDAEKFSDQ | DKQVKERVEV | RNDLESLAYS | IKNQVKDKEK | MGGKLSDDEI | KTIEDAADEA |
| 610 | 620 | 630 | 640 | 650 | |
| IKWMENNPQA | ETSDYKKQKA | NLESVVQPIV | SKLYEGAAPP | PPTESTPKEE | L |