Q23223
Gene name |
mtr-4 (W08D2.7) |
Protein name |
mRNA transport homolog 4 |
Names |
Uncharacterized helicase W08D2.7 |
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_W08D2.7 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q23223
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q23223-F1 | Predicted | AlphaFoldDB |
No variants for Q23223
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q23223 | |||||
No associated diseases with Q23223
6 regional properties for Q23223
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Helicase, C-terminal | 360 - 564 | IPR001650 |
| domain | DEAD/DEAH box helicase domain | 129 - 273 | IPR011545 |
| domain | ATP-dependent RNA helicase Ski2/MTR4, C-terminal | 850 - 1026 | IPR012961 |
| domain | Helicase superfamily 1/2, ATP-binding domain | 122 - 305 | IPR014001 |
| binding_site | EF-Hand 1, calcium-binding site | 492 - 504 | IPR018247 |
| domain | rRNA-processing arch domain | 571 - 824 | IPR025696 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| hydrolase activity | Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| RNA helicase activity | Unwinding of an RNA helix, driven by ATP hydrolysis. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| maturation of 5.8S rRNA | Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule. |
| RNA catabolic process | The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MADLFDEFIE | PGVKNEIMDV | EEAPENPMEK | LDSAKKRQAR | EDMTNLLANM | HNDVGVGNFD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EATSKRARVE | EEEEVEEARM | ENIIVHTIRT | DNENCTHEVA | IPPNAEFAEL | RENSGTEPAK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YYPFQLDAFQ | KQAILCIDNN | QSVLVSAHTS | AGKTVVATYA | IAKCLREKQR | VIYTSPIKAL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SNQKYRELEE | EFKDVGLMTG | DVTLNPDASC | LVMTTEILRS | MLYRGSEIMK | EVGWVVYDEI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| HYMRDKERGV | VWEETIILMS | KNIKQAFLSA | TIPNARQFAQ | WVASIKQQPV | NVVYTDYRPT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PLQHWIYPVG | GEGMYEVVNV | KGEFREDKFR | DAMSGLATAG | DSAGSFNKRR | TGGGTQGDSN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VLKIIRSVAS | NDGLNCIVFS | FSRKECESYA | ISLKDMDFNK | DHEKGMVKSV | YESAIAQLSP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| EDQKLPQILN | ILPLLRRGIG | VHHSGLMPIL | KETIEILFGE | GLVKVLFATE | TFSMGLNMPA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RTVVFTSARK | FDGSDNRYIT | SGEYIQMAGR | AGRRGKDDRG | TVILMVDSAM | SADDAKQIIK |
| 550 | 560 | 570 | 580 | 590 | 600 |
| GATDPLNSQF | RLTYNMVLNL | MRVEGMAVSW | IINNSFHQFQ | SYAKIPEIDK | KCVQVERKIA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| SFNFPWENEM | RTLVDLQDQL | EATRQRIIQI | QREPKYIVGF | LHAGRLFKVK | SGDRDFKWGI |
| 670 | 680 | 690 | 700 | 710 | 720 |
| LNQFKKEQNP | DDRNDQIYLC | DMMIAINTEG | RFDPTNPATL | VPGFDLPKRR | WIRVPMTIDR |
| 730 | 740 | 750 | 760 | 770 | 780 |
| ITAISAVRLK | VPADIDKPDG | QMRLDGMMAA | ATKRFGNQIP | LLDPIQDMEI | KTVEMKELIA |
| 790 | 800 | 810 | 820 | 830 | 840 |
| REKSLEGRLE | THSMTKRDNM | KDLKKQFEQK | QDAVKELNAL | KAERKSVQST | LHLEELNNRK |
| 850 | 860 | 870 | 880 | 890 | 900 |
| RVLRRLGYLG | NDDALVLKGS | VACELSASDE | LILTEMLLKG | IFNTLDVAQT | AALLSCFVFQ |
| 910 | 920 | 930 | 940 | 950 | 960 |
| DKCAAPKLAT | ELQTCLSELH | EQARNVAKVS | NECKMEVMED | KYVSSFNPGL | MDVVYQWVNG |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| ATFSEIVKTT | DVFEGSIIRT | LRRLEEVLRE | MINAAKALAN | KELEQKFEDA | RKNLKRDIVF |
| AASLYL |