Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q23027

Entry ID Method Resolution Chain Position Source
AF-Q23027-F1 Predicted AlphaFoldDB

No variants for Q23027

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q23027

No associated diseases with Q23027

No regional properties for Q23027

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q23027

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
  • Cell junction, gap junction
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
gap junction A cell-cell junction composed of pannexins or innexins and connexins, two different families of channel-forming proteins.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
gap junction channel activity A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes.
gap junction hemi-channel activity A wide pore channel activity that enables the transport of a solute across a membrane via a gap junction hemi-channel. Two gap junction hemi-channels coupled together form a complete gap junction.

1 GO annotations of biological process

Name Definition
ion transport The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9V3W6 Inx7 Innexin inx7 Drosophila melanogaster (Fruit fly) PR
10 20 30 40 50 60
MIGVLLPYVR KFQRSAESND IADRFSYQYT STLLGFSAIM MAASQYVGRP IQCWVPAQFT
70 80 90 100 110 120
RTWEKYAETY CFIKGTYFLP GAFASEGEMS VTSPDDAVTA TPQVGYYQWI PIVLVLQAFL
130 140 150 160 170 180
FYLPSIIWRT FNESCELKIK ELAAVSEASR KIKSNMSDDQ VKATKFGRYF FKKLNFRNES
190 200 210 220 230 240
PVFKETGSVV ASGKFLPALY LLVKILYLAN IVLQFWILTY FLETKSWMWG WQTFQDLMAG
250 260 270 280 290 300
REWETTGIFP RVTMCDFSIM DLTSVHDHSI QCVIVINMLA EKVYVFFWFW LLFVGLLTVC
310 320 330 340 350 360
SLAYWAVIYM LQSVGRNFIY SYLQQTPEFQ TEQERGSFVP ANFVDKCLTP DGVFISRLVQ
370 380 390 400 410 420
QNSGDLFTSI MLGEMFSLYR AREAEKAHKK DDDSALPASA PVDLQEDDDD DTPFPPPTKA
430 440
VAETLTSDDE EEETDVDSPD TTATLPR