Q21XR4

PR
Gene name
argH
Protein name
Argininosuccinate lyase
Names
ASAL, Arginosuccinase
Species
Albidiferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) (Rhodoferax ferrireducens)
KEGG Pathway
rfr:Rfer_1710
EC number
4.3.2.1: Lyases acting on amides, amidines, etc
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-104 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q21XR4

Entry ID Method Resolution Chain Position Source
AF-Q21XR4-F1 Predicted AlphaFoldDB

No variants for Q21XR4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q21XR4

No associated diseases with Q21XR4

3 regional properties for Q21XR4

Type Name Position InterPro Accession
conserved_site Fumarate lyase, conserved site 290 - 299 IPR020557
domain Fumarate lyase, N-terminal 17 - 315 IPR022761
domain Argininosuccinate lyase, C-terminal 390 - 457 IPR029419

Functions

Description
EC Number 4.3.2.1 Lyases acting on amides, amidines, etc
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
argininosuccinate lyase activity Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.

1 GO annotations of biological process

Name Definition
arginine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSHNQFDKKS QAWSALFSEP MSDLVKRYTA SVFFDKRLWQ ADIAGSLAHA DMLAAQKIIS
70 80 90 100 110 120
SEDHNAIQSG MATISAEIES GAFDWKLELE DVHLNIEARL TQLIGLAGKR LHTGRSRNDQ
130 140 150 160 170 180
VATDVRLWLR GEIDLIGALL TDLQKALLEV AEKNVEVILP GFTHLQVAQP ISFGHHMLAY
190 200 210 220 230 240
VEMFSRDAER MSEVRRRTNR LPLGAAALAG TSYPLDRERV AVSLGMVDEK GHPCVCQNSL
250 260 270 280 290 300
DAVSDRDFAI EFTAAASLCM VHISRMSEEL ILWMSQNFGF IKIADRFTTG SSIMPQKKNP
310 320 330 340 350 360
DVPELARGKT GRVVGHLMGL ITLMKGQPLA YNKDNQEDKE PLFDTVDTLK DTLRIFAEMI
370 380 390 400 410 420
GGQLNPATGI KEGGISVNPQ AMEQAALKGY ATATDLADYL VKKGLPFRDA HETVAHAVKA
430 440 450 460 470 480
AITHQVDLSE LPLAVLQQFN PGIEKDVYEV LSLRGSLNAR DILGGTAPNQ VRAQIARHRA
RLG