Q21WM8
Gene name |
mnmC (Rfer_2101) |
Protein name |
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC |
Names |
tRNA mnm(5)s(2)U biosynthesis bifunctional protein |
Species |
Albidiferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) (Rhodoferax ferrireducens) |
KEGG Pathway |
rfr:Rfer_2101 |
EC number |
2.1.1.61: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q21WM8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q21WM8-F1 | Predicted | AlphaFoldDB |
No variants for Q21WM8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q21WM8 | |||||
No associated diseases with Q21WM8
3 regional properties for Q21WM8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | FAD dependent oxidoreductase | 235 - 319 | IPR006076-1 |
| domain | FAD dependent oxidoreductase | 332 - 568 | IPR006076-2 |
| domain | MnmC-like methyltransferase | 83 - 188 | IPR008471 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.61 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| oxidoreductase activity, acting on the CH-NH group of donors | Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. |
| tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing 5-aminomethyl-2-thiouridine = S-adenosyl-L-homocysteine + tRNA containing 5-methylaminomethyl-2-thiouridylate. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVELAAATCL | HECGLPQAWC | KQEAWRILET | RFGQGLHFLT | TWQAWRNDPQ | RPRMLHYVAV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TAAPPDIDEL | LAGMASSPEL | LLLAKELAPQ | CLGLSTGFQR | LTFDGGHVLL | TLCVGDLTAM |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LRAQQFAADS | IYLTPDPTDC | PDRCAASNWR | VWTAKALARC | CRRGTTLVAP | VDADHLYADL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TQCGFELSTI | QAGQPTGPEA | APTNISLRAQ | FNPRWTIKNT | RNTLPARAMA | VSSCAVIGAG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LAGASVAASL | ARRGWQVQVL | DQAHTPAAGA | SGLPVGLVVP | HVSADDCVLS | RLSRSGVRLM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LQQARSLLRQ | GQDWDATGVL | ERRLDGPPGV | PDIWHPQAAW | LKPTQLVRAW | LAQLGITFQG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DAKVAALRQR | GDEWELLDTD | GGMLHRASRV | VFANAGGAMA | LLDTLQARLP | ALNIRVNQFP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VMQGVRGQVS | WAMHTGLPDE | TFPPFPINGA | GSIVPWVPVD | EDCGQNLAWF | VGASYQPDSQ |
| 490 | 500 | 510 | 520 | 530 | 540 |
| PPAPDEKNHA | TNLARLHKLS | PKLGQALAGK | FAAGAVNAWK | NTRCVTADRL | PAVGPLDQVD |
| 550 | 560 | 570 | 580 | 590 | 600 |
| HPGLWMCAGM | GSRGLSFSML | CAELLAARWS | GEPLPIDAGL | ARTLEARRGA | DCHRNRLDRS |
| PELPVSCAP |