Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q21TP7

Entry ID Method Resolution Chain Position Source
AF-Q21TP7-F1 Predicted AlphaFoldDB

No variants for Q21TP7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q21TP7

No associated diseases with Q21TP7

3 regional properties for Q21TP7

Type Name Position InterPro Accession
domain Guanylate kinase-like domain 5 - 183 IPR008144
domain Guanylate kinase/L-type calcium channel beta subunit 4 - 186 IPR008145
conserved_site Guanylate kinase, conserved site 39 - 56 IPR020590

Functions

Description
EC Number 2.7.4.8 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
guanylate kinase activity Catalysis of the reaction: ATP + GMP = ADP + GDP.

1 GO annotations of biological process

Name Definition
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDYPGNLFVV AAPSGAGKSS LVKALLELDS HVQLSVSHTT RAPRGQEKHG REYFFVSEQE
70 80 90 100 110 120
FDAMVKADAF VEWASVHQHR YGTSKRAIEE RMAQGADVVL EIDYQGALQI KKLFANAISI
130 140 150 160 170 180
FILPPSWDEL RARLERRGED SADVIELRLK NAAIEVAQVH KFDFVIINEL FDRALFDLKA
190 200
IVHSQRLKFS AQRRARAETF KALHIF