Q21SF8

PR
Gene name
rpoC
Protein name
DNA-directed RNA polymerase subunit beta'
Names
RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'
Species
Albidiferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) (Rhodoferax ferrireducens)
KEGG Pathway
rfr:Rfer_3591
EC number
2.7.7.6: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1341-1405 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q21SF8

Entry ID Method Resolution Chain Position Source
AF-Q21SF8-F1 Predicted AlphaFoldDB

No variants for Q21SF8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q21SF8

No associated diseases with Q21SF8

7 regional properties for Q21SF8

Type Name Position InterPro Accession
domain RNA polymerase, alpha subunit 342 - 391 IPR000722-1
domain RNA polymerase, alpha subunit 390 - 483 IPR000722-2
domain RNA polymerase, N-terminal 233 - 512 IPR006592
domain RNA polymerase Rpb1, domain 3 487 - 643 IPR007066
domain RNA polymerase Rpb1, domain 1 16 - 340 IPR007080
domain RNA polymerase Rpb1, domain 5 765 - 1314 IPR007081
domain RNA polymerase Rpb1, domain 4 673 - 762 IPR007083

Functions

Description
EC Number 2.7.7.6 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.

4 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
magnesium ion binding Binding to a magnesium (Mg) ion.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKSLLDLFKQ FTPDEHFNAI KIGMASPEKI RSWSFGEVKK PETINYRTFK PERDGLFCAK
70 80 90 100 110 120
IFGPIKDYEC LCGKYKRLKH RGVICEKCGV EVTQTKVRRE RMGHIDLAAP CAHIWFLKSL
130 140 150 160 170 180
PSRLGLVLDM TLRDIERVLY FEAYVVTDPG MTPLKKFSIM SEDDFDAKFK EYGDEFQAKM
190 200 210 220 230 240
GAEGIKDLLQ SLDIDGSIER LRNDPTGSEL KIKKNTKRLK LLEAFKKSGI KPEWMVLEVL
250 260 270 280 290 300
PVLPPDLRPL VPLDGGRFAT SDLNDLYRRV INRNSRLRRL LELKAPEIIA RNEKRMLQEA
310 320 330 340 350 360
VDSLLDNGRR GKAMTGANKR ALKSLADMIK GKSGRFRQNL LGKRVDYSGR SVIVVGPTLK
370 380 390 400 410 420
LHQCGLPKLM ALELFKPFIF ARLEAMGIAT TIKAAKKEVE SGTPVVWDIL EEVIKEHPVM
430 440 450 460 470 480
LNRAPTLHRL GIQAFEPILI EGKAIQLHPL VCAAFNADFD GDQMAVHVPL SVEAQVECRT
490 500 510 520 530 540
LMLASNNVLF PSNGEPSIVP SQDVVLGLYY TTRERINGKG EGLIFADVGE VQRAFDGGAV
550 560 570 580 590 600
ELNSRINVRL TEYIKDKQTG ELVPSTKLWE TTAGRALLSE ILPKGLPFEN VNKALKKKEI
610 620 630 640 650 660
SKLINVSFRK CGLKETVVFA DKLLQYGFRL ATKAGISICL DDMLVPTEKP GIIEQAEQEV
670 680 690 700 710 720
KEIAQQYTSG LVTSGERYNK VVDIWGKAGD EVSKVMMAQL SKEIVTDRHG QQVQQESFNS
730 740 750 760 770 780
IYMMADSGAR GSPAQIRQVA GMRGLMAKPD GSIIETPITA NFREGLNVLE YFISTHGARK
790 800 810 820 830 840
GLADTALKTA NSGYLTRRLV DVTQDLVVTE QDCGTHSGYL MRAIVEGGEV IESLRDRILG
850 860 870 880 890 900
RTAADDVLHP ENRSVLAPAG TMLDEDQIDE LEVAGVDEVK VRTALTCETR FGICAKCYGR
910 920 930 940 950 960
DLGRGGLVNG GEAVGVIAAQ SIGEPGTQLT MRTFHIGGAA SRAAIASSVE AKSNGNIGFN
970 980 990 1000 1010 1020
ATMRYVTNGK KELVVISRSG EIVIHDEHGR ERERHKVPYG AVLAVKADQT IKSGAILANW
1030 1040 1050 1060 1070 1080
DPLTRPIITE FAGKAHFENV EEGLTVAKQV DEVTGLSTMV VIDPKHRGSA KVIRPIVKLI
1090 1100 1110 1120 1130 1140
DASGNEVKIP GTDHSVTIGF PIGALVQVRD GQDVSPGEVL ARIPIEGQKT RDITGGLPRV
1150 1160 1170 1180 1190 1200
AELFEARSPK DKGVLAEMTG TVSFGKETKG KIRLQITDPD GAVWEDLVPK EKNIIVHEGQ
1210 1220 1230 1240 1250 1260
VVNKGESVVD GPADPQDILR LLGSEELARY IVDEVQDVYR LQGVKINDKH IEVIVRQMLR
1270 1280 1290 1300 1310 1320
RVVVENAGDS TYINGEQVER SEILNTNDAL RADGKIPARF TNLLLGITKA SLSTDSFISA
1330 1340 1350 1360 1370 1380
ASFQETTRVL TEAAIMGKRD ELRGLKENVI VGRLIPAGTG MAYHEARKVR ENMDDTERRA
1390 1400
IAEAEAAELA GQAEATEANE GAAAE