Q21NX6

PR
Gene name
gcvH
Protein name
Glycine cleavage system H protein
Names
Species
Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)
KEGG Pathway
sde:Sde_0339
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

84-130 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q21NX6

Entry ID Method Resolution Chain Position Source
AF-Q21NX6-F1 Predicted AlphaFoldDB

No variants for Q21NX6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q21NX6

No associated diseases with Q21NX6

2 regional properties for Q21NX6

Type Name Position InterPro Accession
domain Biotin/lipoyl attachment 24 - 106 IPR000089
binding_site 2-oxo acid dehydrogenase, lipoyl-binding site 49 - 78 IPR003016

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
glycine cleavage complex A protein complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase, also known as L, P, H, and T.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
glycine decarboxylation via glycine cleavage system The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSELRSELKY LESHEWARVE EDGTVTIGIT DHAQEALGDV VFVEVPEVGS QVSIGEEAGV
70 80 90 100 110 120
VESVKAASDI YSPVSGEVIA VNEALEDAPE TVNSSPYDDG WFFKVKPDDL DELEKALSME
DYKAAIESDD