Q21JW7

PR
Gene name
rlmL
Protein name
Ribosomal RNA large subunit methyltransferase K/L
Names
Species
Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)
KEGG Pathway
sde:Sde_1752
EC number
2.1.1.173: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

369-477 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q21JW7

Entry ID Method Resolution Chain Position Source
AF-Q21JW7-F1 Predicted AlphaFoldDB

No variants for Q21JW7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q21JW7

No associated diseases with Q21JW7

3 regional properties for Q21JW7

Type Name Position InterPro Accession
domain Ribosomal RNA large subunit methyltransferase K/L-like, FLD domain 172 - 385 IPR000241
domain THUMP domain 51 - 164 IPR004114
domain S-adenosylmethionine-dependent methyltransferase 553 - 710 IPR019614

Functions

Description
EC Number 2.1.1.173 Methyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
23S rRNA (guanine(2445)-N(2))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(2445) in 23S rRNA = N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine.
RNA binding Binding to an RNA molecule or a portion thereof.
rRNA (guanine-N7-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPTETNQNTT QYDLFVSCSQ GWEGLLQTEL EQLAVGDVKP GHAGVYVSAT LEQMYKICLW
70 80 90 100 110 120
TRLATKVLLP LDSGPIETGD DVHTVASKVD WPSLMKPGAS LKVDFIGTND AVRNTQFGAQ
130 140 150 160 170 180
RVKDAVVDSI RHAGGERPNV EKMQPDVRIH ARLHRDELHI SIDLSGDSLH RRGYRQKQGG
190 200 210 220 230 240
APLKENLAAA LLLRAGWPTI AEQGGALLDP MCGSGTLLIE GALIAYSIAP GLSRDKFGFE
250 260 270 280 290 300
CWTGHNADTW AQVVNDAKAI RDKNLQEKSF DIFGYDSDYY VTKAAEMNCE ALGLQNVIHI
310 320 330 340 350 360
ANKPVEELKQ PTHKVLVPGL VIVNPPYGER LGEVNELRTT YQILAHQVKQ QFEGWTFAVF
370 380 390 400 410 420
TSNPELAKET RLRANKKNKF KNGALPAELF VYSVLSADDA KLRKDKLTQA VQTDEDGQVE
430 440 450 460 470 480
NASGAWVRKN LCDKPLTEAA TMVANRIKKN LKRLKKSVKQ NDWHGYRVYD ADMPEYSAAI
490 500 510 520 530 540
DLYNDQVHIQ EYAAPKTIDA DKAEARFETL KHGAAVALQA PDNKLFVKTR KRNKGKAQYE
550 560 570 580 590 600
KQTDTQGFDA ERCIQVQEGN AKLWVNLQDY LDTGLFLDHR PLRMRIHKEA TGKRFLNLFC
610 620 630 640 650 660
YTATASVQAA LGGATESVSV DMSNTYLEWA DNNFRLNNVH LARHRLVRAD CFDWLNKCRE
670 680 690 700 710 720
GFDLIMLDPP TFSNSKKMSD VLDIQKDQVR LISRCMDILN PGGTLYFSTN FRQFKLDEQI
730 740 750
STRYVVENIS AATIDEDFKG NPKIHYCWKI QH