Q21H61

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)
KEGG Pathway
sde:Sde_2708
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

9-349 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q21H61

Entry ID Method Resolution Chain Position Source
AF-Q21H61-F1 Predicted AlphaFoldDB

No variants for Q21H61

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q21H61

No associated diseases with Q21H61

7 regional properties for Q21H61

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 409 - 578 IPR000795
domain Small GTP-binding protein domain 414 - 568 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 47 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 331 - 382 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 61 - 98 IPR013575
domain Translation initiation factor IF- 2, domain 3 684 - 799 IPR023115
domain Translation initiation factor IF-2, domain II 584 - 679 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAEVTVSELA KSVGAPVERI LSQMQQAGLT HQSPDDVVSD EEKQKLLTFL KSSHGETVAE
70 80 90 100 110 120
PKKITLKRKT TTTLKTGSGS GRKTVNVEVR KKRTYVKRDE VADEIEESAA VAEAEVAKVE
130 140 150 160 170 180
EPVVEPVQEP EVAAEPEVVE APEPEPVVEA IEEAPVEEPA APAAPVISQT TTASSLVDDA
190 200 210 220 230 240
EEMRIRAASA RIKAEEERLA AIEKARKEKA AKPAPAPGPA AAAKEDARPT KHVEDLAKLK
250 260 270 280 290 300
KPHDKKDEEF DEDGKKHNKK AGKAVKKVAG PKKVASALDY VEDKEEIEEV IHAPKPKRLS
310 320 330 340 350 360
ANRGPRPVIK VSNKHGFKKP TGKITYDVEI PETITVGELA QRMNVKAGEV VKCLMKMGTM
370 380 390 400 410 420
ATVNQPIDQE TAQLVVEELG HKAVLISADA IEIKLQEEVA ANVDGETIPR APIVTVMGHV
430 440 450 460 470 480
DHGKTSLLDY IRKAKVASGE AGGITQHIGA YRVQTSHGEL TFLDTPGHAA FTAMRARGAQ
490 500 510 520 530 540
CTDVVILVVA ADDGVMPQTE EAVQHARAAG VPLVVAINKM DKESADPDRV KNELSAKEVI
550 560 570 580 590 600
PEDWGGDTQF IEVSAHTGQG IEELLEAVAL QAELLELSAP KDVPARGVVV ESRMDKGRGV
610 620 630 640 650 660
VATVLVQGGD LKSGDILLAG QSFGRVRAMT NEFGEQVKTA GPSSPVEILG LDTPPQAGDE
670 680 690 700 710 720
FLVVPDERKA REVAEFRAER ERQEKLQRQQ AAKLENMFAG IGENETKVLS VVLKTDVRGS
730 740 750 760 770 780
LEAIQAALLD IGNDEVQVNI VGGGVGGITG NDVNLALTTG AIVLGFNVRA DASARKLAET
790 800 810 820 830 840
ESIEIRYYSI IYQLIDEVKS ALSGMLDPER VEEIVGIAEV RETFRSPKFG QVAGCMVVEG
850 860 870 880 890 900
SVHRNKPIRV LRENVVIFEG ELESLRRFKD DVSEVRNGTE CGIGVKNYDV KVGDQIEVFD
VKEVAREL