Q21DB1

PR
Gene name
tsaD
Protein name
tRNA N6-adenosine threonylcarbamoyltransferase
Names
N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Species
Rhodopseudomonas palustris (strain BisB18)
KEGG Pathway
rpc:RPC_0046
EC number
2.3.1.234: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

192-269 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q21DB1

Entry ID Method Resolution Chain Position Source
AF-Q21DB1-F1 Predicted AlphaFoldDB

No variants for Q21DB1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q21DB1

No associated diseases with Q21DB1

2 regional properties for Q21DB1

Type Name Position InterPro Accession
domain Gcp-like domain 6 - 348 IPR000905
conserved_site Peptidase M22, conserved site 106 - 126 IPR017860

Functions

Description
EC Number 2.3.1.234 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
iron ion binding Binding to an iron (Fe) ion.
N(6)-L-threonylcarbamoyladenine synthase activity Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA.

1 GO annotations of biological process

Name Definition
tRNA threonylcarbamoyladenosine modification The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATDTASLVL GIETTCDETA AAVVERRSDG SGRILSNIVH SQIEDHAPFG GVVPEIAARA
70 80 90 100 110 120
HVDLLDGIIA RAMQQAGLGF KDLSGVAAAA GPGLIGGVIV GLTTGKAIAL VHDTPLIAVN
130 140 150 160 170 180
HLEAHALTPR LTDALQFPYC LFLASGGHTQ IVAVLGVGNY VRLGTTVDDA MGEAFDKVAK
190 200 210 220 230 240
MLGLPYPGGP QVERAAAAGD AARFAFPRPM LGRADANFSL SGLKTAVRNE ASRLSPLEPQ
250 260 270 280 290 300
DVNDLCAGFQ AAALESTADR LHVGLRIFRE RFGAPHALVA AGGVAANQAI RGALQQVALA
310 320 330 340 350 360
AGTQFMIPPP ALCTDNGAMI AWAGAERLAL GLTDSLEFAP RARWLLDANV ITPAQFANTR
AGF