Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q21C27

Entry ID Method Resolution Chain Position Source
AF-Q21C27-F1 Predicted AlphaFoldDB

No variants for Q21C27

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q21C27

No associated diseases with Q21C27

2 regional properties for Q21C27

Type Name Position InterPro Accession
domain Nicotinate phosphoribosyltransferase, N-terminal domain 6 - 125 IPR040727
domain Nicotinate/nicotinamide phosphoribosyltransferase 159 - 385 IPR041525

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFNIHSVEID WGGRPLKLET GKIARQADGA VVATYGETVV LATVVAAKSA KEGVDFLPLT
70 80 90 100 110 120
VDYIEKTYAA GRIPGGYFKR EGRPTEKETL VSRLIDRPIR PLFVDGWRNE TQVIVTVLSH
130 140 150 160 170 180
DMENDPDILA LVASSAALTL SGAPFKGPIG AARVGFINDE YVLNPTLDEM VDTQLDLVVA
190 200 210 220 230 240
GTADAVLMVE SEAKELNEDI MLGAVMFGHR HFQPVVQAII ELAEKAAKEP REVAVVDESV
250 260 270 280 290 300
LEKEILGLIE PELRAAYAIP VKQDRYAAVG KAKEKVMAHY FPEGQEPQYD KLRIAGVFKE
310 320 330 340 350 360
LEAKIVRWNI LDTGKRIDGR DSKTVRNIVA QVGVLPRAHG SALFTRGETQ ALVVTTLGTG
370 380 390 400 410 420
EDEQYIDSLS GTYKETFLLH YNFPPYSVGE TGRMGGTKRR EIGHGKLAWR AIHPVLPPHH
430 440 450 460 470 480
EFPYTLRVVS EITESNGSSS MASVCGASLA LMDAGVPLKR PTAGIAMGLI LEGERFAVLS
490 500 510 520 530 540
DILGDEDHLG DMDFKVAGTE QGITSLQMDI KIAGITEEIM KVALGQAKDG RIHILGEMSK
550 560 570 580 590 600
ALTNARAELG EYAPRIETFK IATDKIREVI GTGGKVIREI VEKTGAKVNI DDDGTVKVAS
610 620 630 640 650 660
SDGESIKAAI KWIKSIASDP ELNAIYDGTV VKVMEFGAFV NFFGAKDGLV HISQLAAGRV
670 680 690 700 710
QKTSDVVKEG DKVKVKLLGF DDRGKTRLSM KVVDQETGED LEAKQKAAEG ATAAE