Q218E3

PR
Gene name
ppc
Protein name
Phosphoenolpyruvate carboxylase
Names
PEPC, PEPCase
Species
Rhodopseudomonas palustris (strain BisB18)
KEGG Pathway
rpc:RPC_1684
EC number
4.1.1.31: Carboxy-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-226 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q218E3

Entry ID Method Resolution Chain Position Source
AF-Q218E3-F1 Predicted AlphaFoldDB

No variants for Q218E3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q218E3

No associated diseases with Q218E3

2 regional properties for Q218E3

Type Name Position InterPro Accession
active_site Phosphoenolpyruvate carboxylase, Lys active site 158 - 169 IPR018129
active_site Phosphoenolpyruvate carboxylase, His active site 582 - 594 IPR033129

Functions

Description
EC Number 4.1.1.31 Carboxy-lyases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
phosphoenolpyruvate carboxylase activity Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + HCO3-.

3 GO annotations of biological process

Name Definition
carbon fixation A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates).
oxaloacetate metabolic process The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle.
tricarboxylic acid cycle A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSKIMPIDP IAQKTPVAED PAAIDEDARL RDDIRLLGRI LGDTVRDQEG EGVFDVVERI
70 80 90 100 110 120
RQTSIRFHRD NDKPARSELE AILDGLSTPD TVRIVRAFSY FSHLANIAED QNNIRQMRAL
130 140 150 160 170 180
SGTPRPGSVV GTLAHARAVG ISAQELRRFF AHALVSPVLT AHPTEVRRKS TMDREMEVAG
190 200 210 220 230 240
LLDRRERLQM TAEEVAQHEE QLRRAVLTLW QTNMLRRTKL TVLDEVKNGL SFYDHSFLRE
250 260 270 280 290 300
VPRLHGLLED RLNDDDGRDE ELASFLRMGS WIGGDRDGNP FVTAEVMRGA LRLQSTRALR
310 320 330 340 350 360
FYLDELHALG SELSIAAHLA DVSDDLRLLA ERSPDTSPHR SGEPYRLAVS GIYARLAATA
370 380 390 400 410 420
HKLKFDDIRA PVGAAEPYAD PQEFKADLDV LHRSLIANQA SVIARGRLRQ LRRAVDCFGF
430 440 450 460 470 480
HLASLDMRQN SAVHERTMTE LIDAAMPGKS YMAMNEEARI ALLAGELRST RPLASPFVKY
490 500 510 520 530 540
GEETLGELAV FRTAAEAHAA FGHTVISQCI ISMCKGVSDM LEVVLLLKEV GLVDHAGRSA
550 560 570 580 590 600
INVVPLFETI EDLQASAGIM DRLLSLHDYR RLVDSRGGVQ EVMLGYSDSN KDGGFVTSGW
610 620 630 640 650 660
ELYKAEIELV KVFEHHGVRL RLFHGRGGSV GRGGGPSYDA ILAQPGGAVN GQIRITEQGE
670 680 690 700 710 720
IITSKYSNAE VGRNNLEILA AATLEASLLM PRQSAPRAEY LDAMEQLSSF AFKAYRGLVY
730 740 750 760 770 780
ETEGFEDYFW ASTVITEIAT LNIGSRPASR KKTHKIEDLR AIPWVFSWAQ CRLMLPGWYG
790 800 810 820 830 840
FGSAVEAFVK EHPDKGMAFL QELYREWPFF RTLLSNMDMV LAKSSIAIAS RYAELVPDEQ
850 860 870 880 890 900
LRQAIFGRIR AEWHGSIQAL LDIMQQDRLL QSNPRLERSI RNRFPYLDPL NHVQVELLKE
910 920
HRSHAIDEKV LRGIQLTING ISAGLRNSG