Q215R8

PR
Gene name
pepA
Protein name
Probable cytosol aminopeptidase
Names
Leucine aminopeptidase, LAP, Leucyl aminopeptidase
Species
Rhodopseudomonas palustris (strain BisB18)
KEGG Pathway
rpc:RPC_2314
EC number
3.4.11.1: Aminopeptidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

116-185 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q215R8

Entry ID Method Resolution Chain Position Source
AF-Q215R8-F1 Predicted AlphaFoldDB

No variants for Q215R8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q215R8

No associated diseases with Q215R8

2 regional properties for Q215R8

Type Name Position InterPro Accession
domain Peptidase M17, leucyl aminopeptidase, C-terminal 184 - 488 IPR000819
domain Peptidase M17, leucyl aminopeptidase, N-terminal 20 - 146 IPR008283

Functions

Description
EC Number 3.4.11.1 Aminopeptidases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
manganese ion binding Binding to a manganese ion (Mn).
metalloaminopeptidase activity Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPDVVNVGFV PMATSARGVL FVFCDDALKF GPDTVKALGT AANAVKRAAA TSQFKGKSGS
70 80 90 100 110 120
TLDILAPEGL KAVRLVVIGA GKLAAIKDHD FLKLGGVLAG KIGGGKEAVT VIAELPTGAM
130 140 150 160 170 180
TPAQGAAVAA GVRMRAYKFD RYKTKKKDGE DTPLNASVAI AVRDVAAAKK AFAPQNHVVD
190 200 210 220 230 240
GVIMARELVN EPPNVLFPVE FARRASQLRK LGVGVEVLDV PAMKRLKMGA LLGVSQGSTQ
250 260 270 280 290 300
PGRTVIMRWN GGKKGEQPVA FVGKGVCFDT GGISIKPSGS MEDMKGDMGG AACVVGLMHA
310 320 330 340 350 360
LAARKAKINV VGAIGLVENM PDGNAQRPGD IVTSMSGQTI EIINTDAEGR LVLADVLWYV
370 380 390 400 410 420
AKKHKPKFMV DLATLTGAIL VALGTEYAGL FSNNDQLSER LTEAGQATGE RVWRLPMGPE
430 440 450 460 470 480
YDKMMDSQFA DMKNAGARHG GSITAAQFLQ RFVDDTPWAH LDIAGTAMGA PKTDINQSWG
490
SGYGVRLLDR LVADYYESK