Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q20374

Entry ID Method Resolution Chain Position Source
AF-Q20374-F1 Predicted AlphaFoldDB

No variants for Q20374

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q20374

No associated diseases with Q20374

No regional properties for Q20374

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q20374

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, P-body
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
P-body A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.

1 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.

3 GO annotations of biological process

Name Definition
deadenylation-dependent decapping of nuclear-transcribed mRNA Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.
determination of adult lifespan The pathways that regulate the duration of the adult phase of the life-cycle of an animal.
P-body assembly The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P25644 PAT1 DNA topoisomerase 2-associated protein PAT1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
10 20 30 40 50 60
MEEVKKYGKT LEEIEGGLMF DDFPESLVDS DEDHNIFDDE FDAANDETFG GGLDNIGENA
70 80 90 100 110 120
ELENYATQTA KLRFDDPVWQ KPSSSDHVAP SASEIPIPFP NFGNGDASDS FKSSFEAESP
130 140 150 160 170 180
FLKKSIWGNG TDGAYNIWGT NFGISSVPAA PTLDLDFGAL LPTPTIQATK EVKSSQIPSM
190 200 210 220 230 240
PSSALTLEDC ERMQMGNKPD SLVDAFKDLQ LGSTPVQPQS AQFSKHPLEA RIAAPGTPAT
250 260 270 280 290 300
ASSQALPTLP TAALSLEELE LQIMKEAQIL KGRQQVPSDM REDNKFSHPP PGFNQNVQPR
310 320 330 340 350 360
MDPSLSPGGM HGMPPSMGTS MPHMGPMMPP QNMQLPRLPP LNPQFLPLIP VWFNAIINNI
370 380 390 400 410 420
QLPMGVPPPP PFLFQLLNHY RNPQLVHAMI MQSSIPPNIR QNGPQFSHPS GPHSPGNRVQ
430 440 450 460 470 480
RKHSGMPSTR TIYDLALDSF AGYMSYKERE WLIRIQFIQC KGSGDPQVDD YYYVTWRDKQ
490 500 510 520 530 540
IANGWTAETK LEEATKEKKE KSSESQKDYL ERISRMNYRE MQKERARERD KERQRERQER
550 560 570 580 590 600
IDRGEDKKLR QTLSDKFATS LGLPSKSSTH NPRHVLDMKA QVESVDNQTK KLSDEERKIA
610 620 630 640 650 660
VAKKLRTMLL RLEGALNILM EVDELRRSSL PEKSQFKDLS SDEKDQEVEK RTTVIINELM
670 680 690 700 710 720
GDDLSKLMQM SKGRAVITRT LKVVEPRDQA RIILALMTAG GLVSKKMYGE IVLDILPVVY
730 740 750 760 770 780
QKVSNLHPDQ FKYLVGALNL DTLKRQLLDS NMFIRDMMMT LFFVSVKNNQ QLVEWAKATK
790 800 810 820 830
FSSLKMPSSA PLSIWRKALS VISDSEIKEF ADDIKYSGIV DCHDVAQLIE QSL