Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q1WUF4

Entry ID Method Resolution Chain Position Source
AF-Q1WUF4-F1 Predicted AlphaFoldDB

No variants for Q1WUF4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1WUF4

No associated diseases with Q1WUF4

6 regional properties for Q1WUF4

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 238 - 407 IPR000795
domain Small GTP-binding protein domain 241 - 397 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 50 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 161 - 209 IPR006847-2
domain Translation initiation factor IF- 2, domain 3 513 - 628 IPR023115
domain Translation initiation factor IF-2, domain II 416 - 508 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVKKRIYELA KELGISSERV IEIAKKYDFK VTNHMSALDE NEQNKIRGSI SLKAKKKEHI
70 80 90 100 110 120
QHNKNKDNFH SKKVQKSNTG SKDENNHKNV HKNNRKRSGS SMKENNNAKN GQRNNRNNRS
130 140 150 160 170 180
NNKFKNKRNN NNKRNNNFKK GNPVPPRKNK PLPETLVYTV GMNVADIAKK IHREPAEIIK
190 200 210 220 230 240
KLFMMGVMVN QNQSLDKDTI ELLAADYGIN AEEKVEVDVS DIDKFFEEEQ NNTEHLEKRP
250 260 270 280 290 300
PVVTIMGHVD HGKTTLLDKL RHTHVTEGEA GGITQHIGAY QVRHDDKIIT FLDTPGHAAF
310 320 330 340 350 360
TNMRARGADI TDITVLVVAA DDGVMPQTIE AINHAKAAGV PIIVAVNKID KPGANPNHVM
370 380 390 400 410 420
EQLTEYELIP ESWGGDTIFV EISAKFGKNL DELLDMILLE AEMLELHANP NQRGAGSVIE
430 440 450 460 470 480
ARLDKGKGSV ASLLVQQGTL HVGDPIVVGN TFGRVRTMVD ARGYDIKKAT PATPVEITGL
490 500 510 520 530 540
NEVPDSGDRF ITFEDEKTAR AAGEKRAERA LLKERSQTNH VTLDNLFDTL KEGELKEVGV
550 560 570 580 590 600
IIKADVQGSV EALAQSFKKI DVEGVRVNII HQAVGAINES DVTLAEASNA IIVGFNVRPT
610 620 630 640 650 660
PLAKQQAESD NVDIRLHRVI YKAIDEIETA MKGMLEPEYQ EKITGQVEIR QTYKVSKLGT
670 680 690 700 710 720
IGGGYVIDGY IRRDSGVRVI RDGIVIYEGK LASLKRFKDD VKEVKQGYEC GLMIEKYNDI
730
KVGDQIEAYI MEEVPVD