Q1RK58

PR
Gene name
pld (pldA, RBE_0175)
Protein name
Phospholipase D
Names
PLD, Choline phosphatase
Species
Rickettsia bellii (strain RML369-C)
KEGG Pathway
rbe:RBE_0175
EC number
3.1.4.4: Phosphoric diester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

6-85 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1RK58

Entry ID Method Resolution Chain Position Source
AF-Q1RK58-F1 Predicted AlphaFoldDB

No variants for Q1RK58

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1RK58

No associated diseases with Q1RK58

2 regional properties for Q1RK58

Type Name Position InterPro Accession
domain Phospholipase D/Transphosphatidylase 142 - 169 IPR001736
domain Phospholipase D-like domain 75 - 191 IPR025202

Functions

Description
EC Number 3.1.4.4 Phosphoric diester hydrolases
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

2 GO annotations of molecular function

Name Definition
N-acylphosphatidylethanolamine-specific phospholipase D activity Catalysis of the release of N-acylethanolamine from N-acyl-phosphatidylethanolamine (NAPE) to generate N-acylethanolamine (NAE).
phospholipase D activity Catalysis of the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate.

2 GO annotations of biological process

Name Definition
lipid catabolic process The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
organophosphate metabolic process The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKRKNKKFTE IFIAFILGIA IGVLGYSDYG TDLINQFKIS HTPPPKIKHY NISQLSRSKV
70 80 90 100 110 120
STCFTPPSGC TKFIADQIDT ARESIYMHAY GMSDSLITAA LIDAQARGVQ VKILLDRSNL
130 140 150 160 170 180
KQKFSKLHEL QRAKIEVGID KVPGIAHNKV IIIDKKKVIT GSFNFTAAAD KRNAENVIVI
190 200
EDAELADSYL QNWLSRKARN G