Q1RGR1

PR
Gene name
clpB (RBE_1372)
Protein name
Chaperone protein ClpB
Names
Species
Rickettsia bellii (strain RML369-C)
KEGG Pathway
rbe:RBE_1372
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

111-184 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q1RGR1

Entry ID Method Resolution Chain Position Source
AF-Q1RGR1-F1 Predicted AlphaFoldDB

No variants for Q1RGR1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q1RGR1

No associated diseases with Q1RGR1

9 regional properties for Q1RGR1

Type Name Position InterPro Accession
domain AAA+ ATPase domain 198 - 343 IPR003593-1
domain AAA+ ATPase domain 601 - 744 IPR003593-2
domain ATPase, AAA-type, core 203 - 335 IPR003959-1
domain ATPase, AAA-type, core 601 - 763 IPR003959-2
domain Clp, repeat (R) domain 3 - 146 IPR004176
conserved_site ClpA/B, conserved site 1 294 - 306 IPR018368
domain Clp ATPase, C-terminal 769 - 858 IPR019489
conserved_site ClpA/B, conserved site 2 635 - 653 IPR028299
domain ClpA/ClpB, AAA lid domain 342 - 442 IPR041546

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.

2 GO annotations of biological process

Name Definition
protein refolding The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
response to heat Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNIDKFTAHA KSAITNCQHI AAKNDHQQIL PLHLLASLFN EDTGIIRTLI NNSGGNLNIL
70 80 90 100 110 120
ADQVQVELNK IPKVQVDGGG TIYSSAELLK VLQRADDLAK NNGDSFVTIE RILEALSFDN
130 140 150 160 170 180
TIAGKILTNN GISSKKLAAS ILQLRKGKKA DTESAENSYD ALKKYGRDVT ELAESGKLDP
190 200 210 220 230 240
IIGRDEEIRR TVQVLSRRMK NNPVLIGEPG VGKTAIIEGL AQRIFSKDVP ETLINCRIIE
250 260 270 280 290 300
LDMGALIAGA KYRGEFEERL KAVLGEIKES SGEIILFIDE LHLLVGTGKT DGAMDASNLL
310 320 330 340 350 360
KPMLARGELH CIGATTLDEY RKYIEKDAAF ARRFQPVYVS EPTVEDTISI LRGIKEKYEL
370 380 390 400 410 420
HHAVRISDSA IVAAATLSNR YITDRFLPDK AIDLIDEACS RMKIELSSKP EELDELDRRI
430 440 450 460 470 480
IQIKIELAAL KKESDEHSKK KIEHLTAELE KLESNSYDMS SKWQAEKSKI QGQQKLKEEL
490 500 510 520 530 540
DRARIDLERA ERDANLAKAS ELKYGIIPEI MKKIQETENA DSKGLLKEIV SESDIASIIS
550 560 570 580 590 600
RITGIPIDTM LSSERERLLV MEQKLRESVI GQDEAIKSVS DAVRRSRAGI QDINRPLGSF
610 620 630 640 650 660
LFLGPTGVGK TELTKALAGF LFDDRNAILR IDMSEYMEKH AISRLIGAPP GYVGYDQGGV
670 680 690 700 710 720
LTEAVRRRPY QVILFDEVEK AHPDIFNIML QILDEGRLTD SQGITVDFKN TIIVLTSNLG
730 740 750 760 770 780
AEILVNQKEG EDTYKVKDQV MEYVKMVFKP EFLNRLDEII LFHRLNQSNI HDIVKIQLEG
790 800 810 820 830 840
LKKILSAQNI ILEFDEPALN YLAEKGYDPS FGARPLKRLI QREIQNNLAK MILAGEVSSG
850
KIVKITAKKE ELKIQIID